ID   A0A238C0F1_9BILA        Unreviewed;       347 AA.
AC   A0A238C0F1;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=Nematode cuticle collagen N-terminal domain-containing protein {ECO:0000259|SMART:SM01088};
GN   ORFNames=X798_02324 {ECO:0000313|EMBL:OZC10575.1};
OS   Onchocerca flexuosa.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Onchocerca.
OX   NCBI_TaxID=387005 {ECO:0000313|EMBL:OZC10575.1, ECO:0000313|Proteomes:UP000242913};
RN   [1] {ECO:0000313|EMBL:OZC10575.1, ECO:0000313|Proteomes:UP000242913}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Red Deer {ECO:0000313|EMBL:OZC10575.1};
RA   Mitreva M.;
RT   "Draft genome of the nematode, Onchocerca flexuosa.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBUNIT: Collagen polypeptide chains are complexed within the cuticle
CC       by disulfide bonds and other types of covalent cross-links.
CC       {ECO:0000256|ARBA:ARBA00011518}.
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DR   EMBL; KZ269985; OZC10575.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A238C0F1; -.
DR   Proteomes; UP000242913; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0042302; F:structural constituent of cuticle; IEA:InterPro.
DR   GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR   InterPro; IPR002486; Col_cuticle_N.
DR   InterPro; IPR008160; Collagen.
DR   PANTHER; PTHR24637; COLLAGEN; 1.
DR   PANTHER; PTHR24637:SF421; COLLAGEN-RELATED; 1.
DR   Pfam; PF01484; Col_cuticle_N; 1.
DR   Pfam; PF01391; Collagen; 2.
DR   SMART; SM01088; Col_cuticle_N; 1.
PE   4: Predicted;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000242913};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        13..37
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          13..65
FT                   /note="Nematode cuticle collagen N-terminal"
FT                   /evidence="ECO:0000259|SMART:SM01088"
FT   REGION          80..347
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        99..129
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        174..207
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   347 AA;  35841 MW;  5327EAE0D18C81DD CRC64;
     MIELQSRIKA YKLIGYSAFF FSFLAILSIC ITLPMVYNYV HHVRQKMISD IEFCKNSVKD
     TWMEVRHLRS NPIELLNRTS RQIGYGTPQE APAPKYESTT RRVQPSTQRA PTRQYTTTRT
     TTRAPPSRFR PSTQAAPAVS GGGCGDCCLP GPPGPQGPPG RVGKPGKPGA AGRPGNPGRP
     PPQPCEPVTP PPCKPCPQGP PGPPGIMGPM GEIGSTGQPG DVGLDGGEGD EGPQGQDGPI
     GPSGPPGPPG EQGTDAPNET LRPGEPGPPG DQGPTGSSGK PGKPGKDGPV GPQGPKGNPG
     ADGKPGRDGN PGQRGPPGEP GPPGEKGLCP KYCANDGGVF FEDGSRR
//