ID   A0A238C1U2_9BILA        Unreviewed;       433 AA.
AC   A0A238C1U2;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Nematode cuticle collagen domain protein {ECO:0000313|EMBL:OZC11364.1};
GN   ORFNames=X798_01780 {ECO:0000313|EMBL:OZC11364.1};
OS   Onchocerca flexuosa.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Onchocerca.
OX   NCBI_TaxID=387005 {ECO:0000313|EMBL:OZC11364.1, ECO:0000313|Proteomes:UP000242913};
RN   [1] {ECO:0000313|EMBL:OZC11364.1, ECO:0000313|Proteomes:UP000242913}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Red Deer {ECO:0000313|EMBL:OZC11364.1};
RA   Mitreva M.;
RT   "Draft genome of the nematode, Onchocerca flexuosa.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBUNIT: Collagen polypeptide chains are complexed within the cuticle
CC       by disulfide bonds and other types of covalent cross-links.
CC       {ECO:0000256|ARBA:ARBA00011518}.
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DR   EMBL; KZ269981; OZC11364.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A238C1U2; -.
DR   Proteomes; UP000242913; Unassembled WGS sequence.
DR   GO; GO:0005581; C:collagen trimer; IEA:UniProtKB-KW.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0042302; F:structural constituent of cuticle; IEA:InterPro.
DR   GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR   InterPro; IPR002486; Col_cuticle_N.
DR   InterPro; IPR008160; Collagen.
DR   PANTHER; PTHR24637; COLLAGEN; 1.
DR   PANTHER; PTHR24637:SF368; CUTICLE COLLAGEN 36; 1.
DR   Pfam; PF01484; Col_cuticle_N; 1.
DR   Pfam; PF01391; Collagen; 2.
DR   SMART; SM01088; Col_cuticle_N; 1.
PE   4: Predicted;
KW   Collagen {ECO:0000313|EMBL:OZC11364.1};
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000242913};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        73..96
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          72..124
FT                   /note="Nematode cuticle collagen N-terminal"
FT                   /evidence="ECO:0000259|SMART:SM01088"
FT   REGION          206..227
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          241..433
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        244..258
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        288..302
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        360..377
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   433 AA;  44320 MW;  BF69D176830B8884 CRC64;
     MGAPPPPPPS PKYYQAVPPD CQLLPLGPPS GRAQQAVDQV KINFANFTLA LPEMKLNDIG
     SNLNDEQVQM RRAAFFAIVV STAAVIASIV TLPMLYSFAQ SFQSHLIAET DFCKSRSRDM
     WQEINLIDKE YRVKREAGTW LFGQFISRAP GTVDYNLGNA GYGNEIPTPY GSKGDGYNDG
     ANNDLYGGSS NGNTYSGSGA NPYSSDTISY SDNGKPEISP GYGPGPLINA EPNVGSFCCP
     CQQGPVGPPG PPGDPGPNGK DGEPGKDGEK GKDGQVMQSA IEAEEPCIIC PPGPPGPAGQ
     AGPKGPQGPK GAEGTRGEDG KKGEPGMIGT VGPVGPLGKE GLPGFAGQPG RLIPIDGPLG
     PVGLPGPPGP PGPKGLPGPD GATEDGPQGP LGDQGTPGSP GQRGLEGQPG LPGERGESGS
     CEHCPEPRTP PGY
//