ID A0A238F1X1_9BASI Unreviewed; 1576 AA.
AC A0A238F1X1;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=BQ2448_243 protein {ECO:0000313|EMBL:SCV68122.1};
GN ORFNames=BQ2448_243 {ECO:0000313|EMBL:SCV68122.1};
OS Microbotryum intermedium.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC Microbotryomycetes; Microbotryales; Microbotryaceae; Microbotryum.
OX NCBI_TaxID=269621 {ECO:0000313|EMBL:SCV68122.1, ECO:0000313|Proteomes:UP000198372};
RN [1] {ECO:0000313|Proteomes:UP000198372}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Jeantristanb JTB J.-T., Ricardo R.;
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19)
CC family. {ECO:0000256|ARBA:ARBA00008170}.
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DR EMBL; FMSP01000003; SCV68122.1; -; Genomic_DNA.
DR STRING; 269621.A0A238F1X1; -.
DR OrthoDB; 8346at2759; -.
DR Proteomes; UP000198372; Unassembled WGS sequence.
DR GO; GO:0005774; C:vacuolar membrane; IEA:UniProt.
DR GO; GO:0015369; F:calcium:proton antiporter activity; IEA:UniProt.
DR Gene3D; 1.20.1420.30; NCX, central ion-binding region; 2.
DR InterPro; IPR004713; CaH_exchang.
DR InterPro; IPR004837; NaCa_Exmemb.
DR InterPro; IPR044880; NCX_ion-bd_dom_sf.
DR InterPro; IPR005185; YccF.
DR PANTHER; PTHR31503:SF10; CATION_H+ EXCHANGER PROTEIN 1-RELATED; 1.
DR PANTHER; PTHR31503; VACUOLAR CALCIUM ION TRANSPORTER; 1.
DR Pfam; PF01699; Na_Ca_ex; 2.
DR Pfam; PF03733; YccF; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000198372};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 567..591
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 802..828
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 927..947
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 954..975
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 987..1013
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1025..1047
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1059..1081
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1093..1113
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1162..1182
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1454..1478
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1490..1511
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1517..1537
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 565..615
FT /note="Inner membrane component"
FT /evidence="ECO:0000259|Pfam:PF03733"
FT DOMAIN 995..1182
FT /note="Sodium/calcium exchanger membrane region"
FT /evidence="ECO:0000259|Pfam:PF01699"
FT DOMAIN 1399..1531
FT /note="Sodium/calcium exchanger membrane region"
FT /evidence="ECO:0000259|Pfam:PF01699"
FT REGION 1..484
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 624..723
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1234..1264
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1312..1334
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..16
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 48..80
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 88..102
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 120..138
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 230..250
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 252..268
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 281..324
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 325..339
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 357..388
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 624..644
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 670..723
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1234..1260
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1313..1330
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1576 AA; 168915 MW; 345348A1F2B3307F CRC64;
MSSPGSSPSP SSSADPVRPV RSPAAIPTET AWTATETDLA RGPRSPVSPT LGLSSSAVSA
PDPHTRQSSS GASQPTRRAG LGSIKTRETL MATENDLESL TVTTPGAPAR RRFNLRHSDD
DDDAEEEEDG DDDDGGLAER DNEGGYFTSM SRTRPPALGG ASHMPPSPAF PGSGSYASAV
SGRGRAKAGP PPTPTPIPGS SRTRSTSAVG LPPVMLAASR RATARSVSRA RLRAGDRDDG
HDDDDDDNNR PALLLASSTR TDRPMSPAPV STDATLLDDR EDDEVSVRDR GEELVRKRMK
ERARVKKEAE KAATRKREIE RAAAMRRTTS SSYYDQSDLE AGQTIGMGLP STAASHAGPS
GEGSTRNRSM SRPPARESTA SYASTLVAQG GRAVTGGHGA GRSSSMAPAS GEEEWAKGGS
RRSIAPSEEG ETWSPMFPGR QLSSLRGMSY TSSARGAPVG EDPSSEQTEE QAAEASTEDG
DMDGEHALRD AFEVDEQTDD DDEINQAEVE YTLKDRQDAI NVEHPFGLPI WKPALYKKDR
SITRNAERAL HDVPSSTVVR HLAPGNLVWT LFFGTALFIV CTLVAGMLWC VPWGGGKYGR
VVWELGGYLF WPFGKYVEGW TDQFDDETSN GSEASGTASA HDQNGAEESL DEEEEMDRAS
LRRDLENAGS TYGRGQSRTR STSSRPCGTS QRRASSFDSS HVGDASETHL TVRGVSSSTS
LRMPGDLAED SRLLAPSGQQ PIYGATATAT MPTSSPRGQG MQCASSEDTV AAPSWRPHDF
SKDSSGSAHR ALRIRALGRT MWWVAFYLIV APLLLLVCVL CWGLVFTIPM AKLLWVLLRH
LNNEPLALHF RSPPKYNALA AAAPTEIESR FKFNAAVPGL DPQAGGSRVG PPTSANASGV
QYPLIAGQRA PPVSRKSVAA AKRHGRLFGP HSTVLLCTYH AMGLQYYKYT IDGVNILFVN
LMSLVFFVIL DYFYVSPRVA AHHLGGVLAF IASPACMFVL ALLSVIPLSY FIGMAVASIS
AQSSIGMGAV INASFGSIIE IILYSIALTR AKGELVEGSI VGSILAGVLL MPGASMIGGA
MRRKEQKFNA RSAGVTSTML IMAIIGILTP TLFYEIYGSF QLTCTDCDPD HRAGTSESCR
TCYYEHINPA DDPFYKSTVK TLSYYCAVLL VLSYLIGLWF SLRTHASQIW QNAQVKHEPL
LPRPLTAAPG PHAPHGDRAS LYKRLVPSQL LPRHRSSTMG RASGSYTPLQ ESTPLITSTN
PELGVPPMVL PEGMSADELH RAFETVAATG VAIAAPSRVA HLPMASASAG SCGGAQMHRS
ASQVREASGA NTNRGAVEHD AGAAEGGHDA PNWSRLKSAS VLLGCTILYA MIAGERVSHQ
NDNAHVRACL NDSSSLLRTE ILVGVVDVVL EGSGIPEKFL GVTLFALVPN TTEFMNAISF
AINGNIALSM EIGSAYALQV CLIQAPAMLA FSAFYSIGKE TLLHRSFTLV FPRWDVIAIM
FSVFLLTYTY IEARANYYRG SILCLSYMVL IGGFAFAPAG RDTSDNPGLW MTSANFVQEL
SVRDHALAIF RALFTR
//
