ID   A0A238F4H5_9BASI        Unreviewed;       872 AA.
AC   A0A238F4H5;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   22-FEB-2023, entry version 18.
DE   RecName: Full=Nitrogen permease regulator 3 {ECO:0000256|RuleBase:RU368069};
DE   AltName: Full=Required for meiotic nuclear division protein 11 {ECO:0000256|RuleBase:RU368069};
GN   ORFNames=BQ2448_5567 {ECO:0000313|EMBL:SCV66921.1};
OS   Microbotryum intermedium.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC   Microbotryomycetes; Microbotryales; Microbotryaceae; Microbotryum.
OX   NCBI_TaxID=269621 {ECO:0000313|EMBL:SCV66921.1, ECO:0000313|Proteomes:UP000198372};
RN   [1] {ECO:0000313|Proteomes:UP000198372}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Jeantristanb JTB J.-T., Ricardo R.;
RL   Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Mediates inactivation of the TORC1 complex in response to
CC       amino acid starvation. Required for meiotic nuclear division.
CC       {ECO:0000256|RuleBase:RU368069}.
CC   -!- SUBCELLULAR LOCATION: Vacuole membrane {ECO:0000256|RuleBase:RU368069};
CC       Peripheral membrane protein {ECO:0000256|RuleBase:RU368069}.
CC   -!- SIMILARITY: Belongs to the NPR3 family. {ECO:0000256|ARBA:ARBA00010546,
CC       ECO:0000256|RuleBase:RU368069}.
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DR   EMBL; FMSP01000001; SCV66921.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A238F4H5; -.
DR   STRING; 269621.A0A238F4H5; -.
DR   OrthoDB; 1381214at2759; -.
DR   Proteomes; UP000198372; Unassembled WGS sequence.
DR   GO; GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-UniRule.
DR   GO; GO:0032007; P:negative regulation of TOR signaling; IEA:InterPro.
DR   InterPro; IPR005365; Npr3.
DR   PANTHER; PTHR13153; CGTHBA PROTEIN -14 GENE PROTEIN; 1.
DR   PANTHER; PTHR13153:SF5; GATOR COMPLEX PROTEIN NPRL3; 1.
DR   Pfam; PF03666; NPR3; 1.
PE   3: Inferred from homology;
KW   Meiosis {ECO:0000256|RuleBase:RU368069};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198372};
KW   Signal {ECO:0000256|RuleBase:RU368069, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           25..872
FT                   /note="Nitrogen permease regulator 3"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5012263390"
FT   REGION          28..101
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          157..261
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          407..455
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          647..796
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        45..73
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        74..97
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        172..193
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        209..230
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        239..261
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        417..431
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        671..693
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        713..785
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   872 AA;  95471 MW;  EB387325C4DFD39E CRC64;
     MVEATASPAS SLLALLLVVK SSRGANLVYQ YPPSPRAVKR TSKPIYHSSR PSTATTVNTR
     RSGYSSDEDD SSNSSSETSS DDDDDDDDDS DDEPRFVDDL DQTERAKAQQ YLGFPSTVLA
     SLLSPSRELC DQPFELVVDH LAFVGHPVWL GDDEPSTGLN RGMSAGRSYH RSGLHGEGDS
     HSEDEDGERR GRTRRRPPLP KPGAFANLSG DFSRSSSEQR GSVSGPLASN PATPPSRPIA
     LMRNSSSTST VHPMSSFASS DNSATAIHGA GRLLAFNFVC VIDTPPDSHL SSHLEGYYKD
     VVIPITANVK ALERQEQWLG KESYKLLKAI EKAHDQGIRN REIPASVATI SPLAEALKRL
     FGALKADQLA NIQLGPLAVQ VLFRGEVPIE EEYDTFYAER QEVHLKDLGP GGIGGGPEQK
     DRHDDPIDAS EAARARSVSP TPSAETYRNH RPPPLFSRMR RRPLVRFQPW ETFLPLEDPD
     ELRKSVQPDT LLSKFLEFCS ANLSFAEYAT LLDIDSDADD GALRDVVQHL VYWRKGKIID
     VVSLKGVYTA SSTLPLASLA QLTFEFGTQF QDLPNLPVLL SKLSPKEPFS SVIPPDSRPL
     RTTYYNALLF LLRNNLVEKQ RTFVRLIAPE SIKNEALRRW GATNASSMDS WSHLSGGGES
     VGKRRLSKVA SSPPGSGTRL SEMSTSVGAV RSRAMSSISI GDGEERLRLQ AEGSESGMST
     PHRGSLSGVS HVASSPPAMM NLLSRSSGSR SGFHLGVQGP QKRTTTGKPP RSSTTWSSSS
     GMPGDVGDAS QVLKGPSVIV EPGRPTMLES RWIAEMTRDV DEGLKERFER MRPFLNGSHH
     LDEVRHRSSL TRRDVRLVLS KFEPYLIVFT HP
//