ID A0A238F706_9BASI Unreviewed; 481 AA.
AC A0A238F706;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=BQ2448_5265 protein {ECO:0000313|EMBL:SCV67654.1};
GN ORFNames=BQ2448_5265 {ECO:0000313|EMBL:SCV67654.1};
OS Microbotryum intermedium.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC Microbotryomycetes; Microbotryales; Microbotryaceae; Microbotryum.
OX NCBI_TaxID=269621 {ECO:0000313|EMBL:SCV67654.1, ECO:0000313|Proteomes:UP000198372};
RN [1] {ECO:0000313|Proteomes:UP000198372}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Jeantristanb JTB J.-T., Ricardo R.;
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Fe(2+); Xref=ChEBI:CHEBI:29033;
CC Evidence={ECO:0000256|PIRSR:PIRSR604574-2};
CC Note=Binds 1 Fe(2+) ion per subunit. {ECO:0000256|PIRSR:PIRSR604574-2};
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DR EMBL; FMSP01000002; SCV67654.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A238F706; -.
DR STRING; 269621.A0A238F706; -.
DR OrthoDB; 47845at2759; -.
DR Proteomes; UP000198372; Unassembled WGS sequence.
DR GO; GO:0051213; F:dioxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR Gene3D; 2.60.120.590; Alpha-ketoglutarate-dependent dioxygenase AlkB-like; 1.
DR InterPro; IPR004574; Alkb.
DR InterPro; IPR027450; AlkB-like.
DR InterPro; IPR037151; AlkB-like_sf.
DR InterPro; IPR005123; Oxoglu/Fe-dep_dioxygenase.
DR PANTHER; PTHR16557; ALKYLATED DNA REPAIR PROTEIN ALKB-RELATED; 1.
DR PANTHER; PTHR16557:SF2; NUCLEIC ACID DIOXYGENASE ALKBH1; 1.
DR Pfam; PF13532; 2OG-FeII_Oxy_2; 1.
DR SUPFAM; SSF51197; Clavaminate synthase-like; 1.
DR PROSITE; PS51471; FE2OG_OXY; 1.
PE 4: Predicted;
KW Dioxygenase {ECO:0000256|ARBA:ARBA00022964};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Iron {ECO:0000256|PIRSR:PIRSR604574-2};
KW Metal-binding {ECO:0000256|PIRSR:PIRSR604574-2};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000198372}.
FT DOMAIN 350..478
FT /note="Fe2OG dioxygenase"
FT /evidence="ECO:0000259|PROSITE:PS51471"
FT REGION 1..45
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 368
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604574-2"
FT BINDING 370
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604574-2"
FT BINDING 425
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604574-2"
SQ SEQUENCE 481 AA; 54507 MW; CC27D97B24F96C54 CRC64;
MTISPPVAST SNISEPSPTL TSKQRRQRQI PQGTAPTNDS AFRTSERYWK NRSQPLNLER
ALSYDRIRWD EDGDEDRWHG VWEDGQGLRV HCFRIRLRVD GDESGCALGQ GRWKGKEVHK
QGQEDSTVRD YAVIIPSMPG IVLFPSILPP KLQRSLVRES LRHSVSPNLT SLSPHYDLPS
EGVWNAFEAG HGARICKRIS LKSDGTIGRD QVNFEPVTKT NWKYEIGRGE KDKDKENVVV
QLRREEPKKE LVILAHTDEA ATSPAAAAAD YAVQDLLTKL RWTTIGWNYD WTSKVYNFEL
PHSNLPPLIH RCCKEAVRRV EWDQVFLGTG EAEWHEGKEN MWDKWREEYE PDAGIVNFYQ
LRDTLTAHID HSELDAVQPL VSFSIGHSAI FLIGGATREI TPLAIELQSG DGLIMSGQRG
RRVFHGIPRI LTDSLPSYLA SNLDLTEHDA GEEGEDWKVF GEFLETGARI NFNVRTVGYT
A
//
