ID A0A238FB22_9BASI Unreviewed; 703 AA.
AC A0A238FB22;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 22-FEB-2023, entry version 17.
DE RecName: Full=Pescadillo homolog {ECO:0000256|HAMAP-Rule:MF_03028};
DE AltName: Full=Nucleolar protein 7 homolog {ECO:0000256|HAMAP-Rule:MF_03028};
GN Name=NOP7 {ECO:0000256|HAMAP-Rule:MF_03028};
GN ORFNames=BQ2448_1799 {ECO:0000313|EMBL:SCV70405.1};
OS Microbotryum intermedium.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC Microbotryomycetes; Microbotryales; Microbotryaceae; Microbotryum.
OX NCBI_TaxID=269621 {ECO:0000313|EMBL:SCV70405.1, ECO:0000313|Proteomes:UP000198372};
RN [1] {ECO:0000313|Proteomes:UP000198372}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Jeantristanb JTB J.-T., Ricardo R.;
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the NOP7 complex, which is required for
CC maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S
CC ribosome. {ECO:0000256|HAMAP-Rule:MF_03028}.
CC -!- SUBUNIT: Component of the NOP7 complex, composed of ERB1, NOP7 and
CC YTM1. Within the NOP7 complex ERB1 appears to interact directly with
CC NOP7 and YTM1. The NOP7 complex also associates with the 66S pre-
CC ribosome. {ECO:0000256|HAMAP-Rule:MF_03028}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000256|HAMAP-
CC Rule:MF_03028}. Nucleus, nucleoplasm {ECO:0000256|HAMAP-Rule:MF_03028}.
CC -!- SIMILARITY: Belongs to the pescadillo family. {ECO:0000256|HAMAP-
CC Rule:MF_03028}.
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DR EMBL; FMSP01000005; SCV70405.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A238FB22; -.
DR STRING; 269621.A0A238FB22; -.
DR OrthoDB; 169151at2759; -.
DR Proteomes; UP000198372; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0030687; C:preribosome, large subunit precursor; IEA:UniProtKB-UniRule.
DR GO; GO:0043021; F:ribonucleoprotein complex binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000466; P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:UniProtKB-UniRule.
DR GO; GO:0000463; P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:UniProtKB-UniRule.
DR CDD; cd17709; BRCT_pescadillo_like; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR HAMAP; MF_03028; Pescadillo; 1.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR010613; PES.
DR PANTHER; PTHR12221; PESCADILLO - RELATED; 1.
DR PANTHER; PTHR12221:SF6; PESCADILLO HOMOLOG; 1.
DR Pfam; PF16589; BRCT_2; 1.
DR Pfam; PF06732; Pescadillo_N; 2.
DR SMART; SM00292; BRCT; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR PROSITE; PS50172; BRCT; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|HAMAP-Rule:MF_03028};
KW Reference proteome {ECO:0000313|Proteomes:UP000198372};
KW Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517, ECO:0000256|HAMAP-
KW Rule:MF_03028};
KW rRNA processing {ECO:0000256|ARBA:ARBA00022552, ECO:0000256|HAMAP-
KW Rule:MF_03028}.
FT DOMAIN 396..494
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT REGION 348..372
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 508..589
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 534..566
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 703 AA; 78308 MW; 663C9904CEE46430 CRC64;
MARITRAHNG MKKKGEAGAA KNYITRNQAI KKLQCTLSDF RRLCILKGIY PREPKSRKKA
NKGSTIPASF YYAKDIQYLL HEPVLGKLRE HKAFAKKLSR AIGRGEWHLA KNLEESKPVY
RLDHIIKERC DTRQAYPTFT DSLRDLDDAL CLIVLFASLP ATTTIPAAII SNCTQLAAQW
QLYVMRTRSL RKVFLSIKGI YFQAEVQGQT VTWLVPYMFT QTVSYLGFAP KGTLWEGWWL
RFDLLFSQIP SDLDYRIMLT FLELYQTLLG FVFYKLYTDI NLIYPPKLDQ VLDEHGAGIG
ALLLEENGQG LVVVRDDAAQ APESIGTERR KPNAKDVRKQ IKQIGLGGNE AQPALEDDEQ
RASAAASNDA SAAQELDVFP SNGAGDEALQ PEATSAATSL FEGYFFYLSR EVTRPTLEFV
IRSLGGQVGW DAVLGAGSPF EENDVRITHH VVDRPVVAGA PPRSHPGKRA YIQPQWVVDC
INRRTLLPTD QYAPGQVLPP HLSPFVDEDE VRERDGYVPM EARRIGGINT VDADMDAEQE
EEEDEDEDDA EEGEGEDEEM DEDEGADEVA TKGKKGKKPA PALLAAAKDP KNAALLHAAE
LEAESRGVEP AQFEAELASE TKKAKKDAAG AGGKVIKAPK KVLRSQEEQL ASIMLTGKQK
KLYSKMVYSK DRRAEETAKL VARKRELEKK QQKRGIKGSQ VGL
//
