ID   A0A238FJL5_9BASI        Unreviewed;       499 AA.
AC   A0A238FJL5;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   13-SEP-2023, entry version 18.
DE   RecName: Full=Phosphotransferase {ECO:0000256|RuleBase:RU362007};
DE            EC=2.7.1.- {ECO:0000256|RuleBase:RU362007};
GN   ORFNames=BQ2448_4887 {ECO:0000313|EMBL:SCV72193.1};
OS   Microbotryum intermedium.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC   Microbotryomycetes; Microbotryales; Microbotryaceae; Microbotryum.
OX   NCBI_TaxID=269621 {ECO:0000313|EMBL:SCV72193.1, ECO:0000313|Proteomes:UP000198372};
RN   [1] {ECO:0000313|Proteomes:UP000198372}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Jeantristanb JTB J.-T., Ricardo R.;
RL   Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the hexokinase family.
CC       {ECO:0000256|ARBA:ARBA00009225, ECO:0000256|RuleBase:RU362007}.
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DR   EMBL; FMSP01000008; SCV72193.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A238FJL5; -.
DR   STRING; 269621.A0A238FJL5; -.
DR   OrthoDB; 5481886at2759; -.
DR   UniPathway; UPA00109; UER00180.
DR   Proteomes; UP000198372; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0005536; F:glucose binding; IEA:InterPro.
DR   GO; GO:0004396; F:hexokinase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006096; P:glycolytic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0001678; P:intracellular glucose homeostasis; IEA:InterPro.
DR   CDD; cd00012; NBD_sugar-kinase_HSP70_actin; 1.
DR   Gene3D; 3.30.420.40; -; 1.
DR   Gene3D; 3.40.367.20; -; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR001312; Hexokinase.
DR   InterPro; IPR022673; Hexokinase_C.
DR   InterPro; IPR022672; Hexokinase_N.
DR   PANTHER; PTHR19443:SF30; GLUCOKINASE-1-RELATED; 1.
DR   PANTHER; PTHR19443; HEXOKINASE; 1.
DR   Pfam; PF00349; Hexokinase_1; 1.
DR   Pfam; PF03727; Hexokinase_2; 1.
DR   PRINTS; PR00475; HEXOKINASE.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR   PROSITE; PS51748; HEXOKINASE_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU362007};
KW   Glycolysis {ECO:0000256|RuleBase:RU362007};
KW   Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000256|RuleBase:RU362007};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW   ECO:0000256|RuleBase:RU362007};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198372};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU362007}.
FT   DOMAIN          24..224
FT                   /note="Hexokinase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00349"
FT   DOMAIN          231..487
FT                   /note="Hexokinase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF03727"
SQ   SEQUENCE   499 AA;  54542 MW;  8FDE3DEB672A4806 CRC64;
     MSPSYLLPLS QGATDLPEKH QQALREIEQQ FDLPTDKLQA IVKQMLWEFE QGLTQVVTAE
     NKDTFMPMIP SYIQSIPSGK EQGTFLALDL GGTNLRVCEV NLLGDSKWTM RQQKYKVSDA
     LKTGEVTHLF DYIATSVDQF LTEIGTSGAK DEKLYLGFTF SFPVAQTALA KGTLINWTKG
     FECKNAVGKD VAQLLQDALD RKHIHVRVSA LVNDTCGTLM AAAYERGNCL CGGIFGTGTN
     GAYVEEMEKI TKMKHSKKDI DDAKKTGLHK MVVNTEWGAF DNERTVMPFT VFDSRVDRIS
     INPRKQAFEK MISGMYLGEV TRNVVLHLVD TQTIFNGFSS KNLNAHYGLD TAIMSALEAP
     SLGGDAAKDA LGTIRQCLTK DLGIENSLVS NADCIAVARV SEIVGTRGAR LSACAIAAVV
     KQTGYDKSGT SEMARFGLDG SLVEFYPRFE QRVRQALKEL LGEEVEKRVA IDLAKDGSGV
     GAALCAQAAK AMEDKAKQA
//