ID A0A238FL94_9BASI Unreviewed; 2656 AA.
AC A0A238FL94;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=BQ2448_7475 protein {ECO:0000313|EMBL:SCV73549.1};
GN ORFNames=BQ2448_7475 {ECO:0000313|EMBL:SCV73549.1};
OS Microbotryum intermedium.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC Microbotryomycetes; Microbotryales; Microbotryaceae; Microbotryum.
OX NCBI_TaxID=269621 {ECO:0000313|EMBL:SCV73549.1, ECO:0000313|Proteomes:UP000198372};
RN [1] {ECO:0000313|Proteomes:UP000198372}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Jeantristanb JTB J.-T., Ricardo R.;
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FMSP01000018; SCV73549.1; -; Genomic_DNA.
DR STRING; 269621.A0A238FL94; -.
DR OrthoDB; 1356198at2759; -.
DR Proteomes; UP000198372; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProt.
DR Gene3D; 3.40.525.10; CRAL-TRIO lipid binding domain; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR001251; CRAL-TRIO_dom.
DR InterPro; IPR036865; CRAL-TRIO_dom_sf.
DR InterPro; IPR039360; Ras_GTPase.
DR InterPro; IPR023152; RasGAP_CS.
DR InterPro; IPR001936; RasGAP_dom.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR PANTHER; PTHR10194:SF142; NEUROFIBROMIN; 1.
DR PANTHER; PTHR10194; RAS GTPASE-ACTIVATING PROTEINS; 1.
DR Pfam; PF13716; CRAL_TRIO_2; 1.
DR Pfam; PF00616; RasGAP; 2.
DR SMART; SM00323; RasGAP; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS00509; RAS_GTPASE_ACTIV_1; 1.
DR PROSITE; PS50018; RAS_GTPASE_ACTIV_2; 1.
PE 4: Predicted;
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000198372}.
FT DOMAIN 1298..1494
FT /note="Ras-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50018"
FT REGION 1..74
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 86..120
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 469..492
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 20..34
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 47..74
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2656 AA; 289913 MW; 59BBB6CDBBB3856C CRC64;
MVELRLLRRG RPSITPVPPS PATTTTTATG TSSSHHDSKD SRPSTSFDYP ERTSSHYQLA
TSPSPTPDTP ANAGTAVVMT TTTTTAKTTS NGPLHQQFGS RRSTSTSTAP VALYTTGPKE
SSRTKMINKI IHQITLHLPS HSTSRHRTGY PSVGQRATRE ATKGLEGACR NPGAIEEVLS
GLLRELERPG SSERGEGARN MSSVASAPLL SSLDVLRSHR ELLRITSSCL LVHWWSHIQR
SSTPTEPTLD PPALDEILAR SLLNVVVPRK SYVPSSISVF STSPSYTSDL VLRVFRSLEA
TPTRHVADLI DSPFSSSETR EDLRFDIHHY SALVLYFLSA SNWPLIHDLL RQRLTGHYGT
GAPPNEVPSS NGTAMDLEAH DLRILESCCF SRSRLSSVFQ DVFNAFLHLR KPARLVLVHT
LRLSVWSWIT SRPAEYRAMV QSGRRLEGGC DMLFDLLWAQ SAILVPEPLS SAPSTSTPTA
TSQNLTRRMS PTPSSLWSTM MMLLLCCPDI VQQLTNHEDA AATNKPAGGY SKKKQFLDGI
KAALSDPVGG YSDHIWHTCV DLLMASHQIV DPSSSIGALA SDCTKGFAKS LMHAICEASI
QRSTLTRCLV ALARLQIIEE SDLIKLLGSL MEPASPFSQQ LGAVNALLIL FSDPISPRSC
SSISKSLGIL FSHATRLPRP IRRARQGSAG SLHTDSSTAV EDASPDLIRS ILVLWSNAPH
FLVNDAGKTL VAVAEMARDL LDETIDRLAF GMILAAFQSY EGRPGPGDDA VDWSLLGKII
AHRILEADDA TMAHCLLLRV LLEIIKRPPW KKAASAGKWS EAFWNALEAS LLVSALSPSD
EISELALECA HQILVVHGAA VPSRTIVKPL GQARDIASKP DMLLSLKLYI RDVDEASMGL
VIAWDELTRR ANDLVGTHLL HHKSPTPHEA TSNMAGSLEI NHWSSLTGVL LVMSGVCTRK
AGPDEGSGGV VDSRLARRND RARQANAIVH ELLEQIVIDD PIVRTHATEL LANNLDIRQL
GAFVMELKKS AQRLLATDHP ESKSANPVFT NMLFVAQSLM ILQALVARVD AGALHREVYN
PMIELLVLLA ELITALPIQD ERLRLQNKLS ALCEHVHAKS VELDETSASK RTKVLEYLYR
WVAVSEDRAG QRAFSSLLRG LKLQTHDGSP DRALFNRYFD HFTRVLSDMA DRPELDPRIA
ADVTRTRSSL MEGFAALLSS NQELAAQRIP EMTCSGLQET LRHIYLEVLT LLLNRGVKFD
SDDGSTSTES AYNQIFQLIR HNPSSLALAL CEVCPPAKYD DLIEVLLRVM SSPSATVSFL
RAVIAAEVSA TDHESTLFRG NTLASRLLTI YSKVQGYHYL RETLRDLLLT ICSKPPEFNL
DFDPHRDSSE DDVASRNLIQ VTEAFLVRIA QSANVAPDMI REICALIAEA VGARFPESVF
TAIGGFIFLR FINPAIVSPE MIDLDLVNQT AGNDTREVRK ALVSVSKILQ ALANNVRFGA
KEPGMRAINP FMDRNIFTMT SFLSSMSRPP SALRIEPLDS VDQDRLNPAN LAFLHTFLVD
NCSKIGSKLL SYPDCEANDL WERLTGLVAA LGPVKRVESV VSRPAERTNE NLAAFMAQNA
FRINMNEAKR WSDIFYRSSV TAHPRAALFV FIPASINAET VDVEGLVFWV LHCLTTVETE
QWDLLVDFTG SSNANILNPV HMQRFLGFVP ESIFKRLSQV VLHSPNFFTQ AYLRRVETRM
GPLDLRMVVA CHHLEDLARF LPTSALPAST LALASESRVT FDRITLKHPV KVEVPVLLQL
DSTAAYLTTV KPHPLAWDLA SVFCEMAPFH LIDDVRLTCT TRYGDEIRVR MRDKEKCWTL
LVESGAADLL NELRARCSGT TTRALLGPQA IPSVRSDRAP LACISSLAIV SCASSKAGLR
SDGYRLARAL GKALGAFEGM SDLPGSYLPS GDLVHLSSLS ETLSPALSPQ LALDVVEELV
EVIATAGPSL TQAISSIYAL RPWLHYLPNA LLVPTEQISK ARFRLRHVFR PLLRKSVEDP
HLCAALTARF WPAVGRLEAI HDLVLDQALD LVPREELGAT EALATRYGDV LATLAAGPSF
RGRVLGRIRR ALAAKAASSN TVAIPIANAA QTKQDLLIVI AVRFDLSLSF ESKISTQILL
PEIVHIVMCL AGEGSVSQRQ TLRQLVQNTI SSLALDDQAD RKRLLDLSKA FESEAVLELM
GLRPRGAGAV ADWDVVRHGE RLATALGEIV EAGAPSPDTE NAWRTRWASL TSTLCFQYDP
ALQARAVATL SYLGSTALDD DVLFQLLTTL GNAIASAEGV ELAALLARCL SKTLQPESKF
LLATTETAMA LLLARPTVVN RPAVTLLAVA IEKLQVSGAF FDTGALEMLG ELWLAHDVQL
MSGQIGVNFE LDVGFALASL LAQPSMDSKT GSDATYCLLS IIHHSHRLVE GEKDVQTQKP
RWLGPFIALL PTLVEQGRLP ELLSAARIDT PPRLSNMPAI VSKLEIPDHN AALMCVALST
RLLEDAVSDA AAAALLQVIA RTLTLYPDLG SLFSETLART LDTCLARPSS EPLLYDAINS
IPPGPTASTF SDAALLDQLN RLGFGSLALK AARRGYSIEL GGGNDWVSTT DEEAQGVTDH
GRANLISTII SQALAA
//
