ID   A0A238FSC6_9BASI        Unreviewed;       763 AA.
AC   A0A238FSC6;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=Translation initiation factor eIF2B subunit epsilon {ECO:0000256|ARBA:ARBA00044144};
DE   AltName: Full=eIF2B GDP-GTP exchange factor subunit epsilon {ECO:0000256|ARBA:ARBA00044345};
GN   ORFNames=BQ2448_6570 {ECO:0000313|EMBL:SCV74138.1};
OS   Microbotryum intermedium.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC   Microbotryomycetes; Microbotryales; Microbotryaceae; Microbotryum.
OX   NCBI_TaxID=269621 {ECO:0000313|EMBL:SCV74138.1, ECO:0000313|Proteomes:UP000198372};
RN   [1] {ECO:0000313|Proteomes:UP000198372}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Jeantristanb JTB J.-T., Ricardo R.;
RL   Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC       {ECO:0000256|ARBA:ARBA00004514}.
CC   -!- SIMILARITY: Belongs to the eIF-2B gamma/epsilon subunits family.
CC       {ECO:0000256|ARBA:ARBA00007878}.
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DR   EMBL; FMSP01000020; SCV74138.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A238FSC6; -.
DR   STRING; 269621.A0A238FSC6; -.
DR   OrthoDB; 5474157at2759; -.
DR   Proteomes; UP000198372; Unassembled WGS sequence.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0031369; F:translation initiation factor binding; IEA:InterPro.
DR   CDD; cd11558; W2_eIF2B_epsilon; 1.
DR   Gene3D; 1.25.40.180; -; 1.
DR   Gene3D; 2.160.10.10; Hexapeptide repeat proteins; 1.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   InterPro; IPR011004; Trimer_LpxA-like_sf.
DR   InterPro; IPR003307; W2_domain.
DR   InterPro; IPR044123; W2_eIF2B_epsilon.
DR   PANTHER; PTHR45887; TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON; 1.
DR   PANTHER; PTHR45887:SF1; TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON; 1.
DR   Pfam; PF02020; W2; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
DR   SUPFAM; SSF51161; Trimeric LpxA-like enzymes; 1.
DR   PROSITE; PS51363; W2; 1.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198372}.
FT   DOMAIN          588..758
FT                   /note="W2"
FT                   /evidence="ECO:0000259|PROSITE:PS51363"
SQ   SEQUENCE   763 AA;  83244 MW;  23D3DC33BBDDF012 CRC64;
     MASKGGALSK EDTKQEHPLQ AIVLCDGWGE EERWGPLVRR KRTDEEEYDD APVGGEQRPW
     CLLPLLGSPL LAWTLECLTA NGVEQIFIFV RDGVDQVKTW LARSTLQQSQ GAFTIVVRPT
     KAATPGDVLR EVDSLQILAP ADFLVVQAGY VGNLNLKGKV TEFAARRKAD PNMCMSCVVA
     PVETRTTPTF AILALSGSYQ LMHYEQSPLF PALRKAKLPR EALDDGKELQ VRADLESVGV
     AICSVEVSRS THHFSDIFAD TWGAVQQVPP LFTENFDYQT FYPDFVNGIL TSDLLGKTIG
     ATVVGEDSIP LVDAQPASEA FSAAATTSGR TPAPWAAVVG NTKSYDAISR AILSRRAYPL
     APDESLPEAR PRFEQRRARV YYGSELDLSR TCRITSTSLI GSYVAIGNAS LVQRSVLDDH
     VHLGSNASVI DSYVLEGANI GDRCVIQNSI IGEDAVISEG CVVEGGCMIA AGVTIGEGSM
     LRACRVSLEE PEYDVNYGEN HLAPGSTGYL WPTEDAQLAA DNLTDDEGEA IDSRNLSVTR
     LGRSLSHLSF HSSTSSLSSL SRASSATSLS ELNEPSVEIQ GLSSLVGAST TTDFLSECHS
     SLERSFAENH TVENAAIELK TLRMASNVPL MRVREVVIPF VLKRCLVDPN KTLAVLERWG
     GLIANLTAEQ EEGMKDSLLI AQEWVAEKVE DEKEGMRMWL RVLKAFYETD VVDDESVFAW
     YKSTEARSVG GEVGRKLWAG AKPFLEAIAQ EEDSDEEDKE DDE
//