GenomeNet

Database: UniProt
Entry: A0A238HEU3_9NEIS
LinkDB: A0A238HEU3_9NEIS
Original site: A0A238HEU3_9NEIS 
ID   A0A238HEU3_9NEIS        Unreviewed;       343 AA.
AC   A0A238HEU3;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   08-MAY-2019, entry version 7.
DE   RecName: Full=Phospho-2-dehydro-3-deoxyheptonate aldolase {ECO:0000256|PIRNR:PIRNR001361};
DE            EC=2.5.1.54 {ECO:0000256|PIRNR:PIRNR001361};
GN   Name=aroG {ECO:0000313|EMBL:SMQ12037.1};
GN   ORFNames=KEBURONENSIS_00950 {ECO:0000313|EMBL:SNB61995.1},
GN   KEBURONENSIS_01046 {ECO:0000313|EMBL:SMQ12037.1};
OS   Kingella negevensis.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales;
OC   Neisseriaceae; Kingella.
OX   NCBI_TaxID=1522312 {ECO:0000313|EMBL:SMQ12037.1};
RN   [1] {ECO:0000313|EMBL:SMQ12037.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Kingella_eburonensis {ECO:0000313|EMBL:SMQ12037.1};
RA   Song R., Chenine A.L., Ruprecht R.M.;
RL   Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:SNB61995.1, ECO:0000313|Proteomes:UP000215450}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Kingella_eburonensis {ECO:0000313|EMBL:SNB61995.1};
RA   Kim H.J., Triplett B.A.;
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Stereospecific condensation of phosphoenolpyruvate (PEP)
CC       and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-
CC       arabino-heptulosonate-7-phosphate (DAHP).
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-
CC         phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate;
CC         Xref=Rhea:RHEA:14717, ChEBI:CHEBI:15377, ChEBI:CHEBI:16897,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58394, ChEBI:CHEBI:58702;
CC         EC=2.5.1.54; Evidence={ECO:0000256|PIRNR:PIRNR001361};
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; chorismate
CC       biosynthesis; chorismate from D-erythrose 4-phosphate and
CC       phosphoenolpyruvate: step 1/7. {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- SIMILARITY: Belongs to the class-I DAHP synthase family.
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; FXUV01000013; SMQ12037.1; -; Genomic_DNA.
DR   EMBL; FXUV02000015; SNB61995.1; -; Genomic_DNA.
DR   UniPathway; UPA00053; UER00084.
DR   Proteomes; UP000215450; Unassembled WGS sequence.
DR   GO; GO:0003849; F:3-deoxy-7-phosphoheptulonate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0009423; P:chorismate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR006218; DAHP1/KDSA.
DR   InterPro; IPR006219; DHAP_synth_1.
DR   PANTHER; PTHR21225; PTHR21225; 1.
DR   Pfam; PF00793; DAHP_synth_1; 1.
DR   PIRSF; PIRSF001361; DAHP_synthase; 1.
DR   TIGRFAMs; TIGR00034; aroFGH; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Aromatic amino acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Complete proteome {ECO:0000313|Proteomes:UP000215450};
KW   Reference proteome {ECO:0000313|Proteomes:UP000215450};
KW   Transferase {ECO:0000256|PIRNR:PIRNR001361,
KW   ECO:0000256|SAAS:SAAS00080156, ECO:0000313|EMBL:SMQ12037.1}.
FT   DOMAIN       35    332       DAHP_synth_1. {ECO:0000259|Pfam:PF00793}.
SQ   SEQUENCE   343 AA;  38065 MW;  BD27CEFFE660BCC6 CRC64;
     MKTDDVRIHA VTELLPPIAH LYELPISEQA SELVYNTRRQ IADLVSGKDN RLLVIIGPCS
     IHDPKAAMEY AQRLLPLRKK YEKELLIVMR VYFEKPRTTV GWKGLINDPH LDGSFDINFG
     LRQARKLLLD LNNMGMPAST EFLDMITPQY YADLISWGAI GARTTESQVH RELSSGLSCP
     VGFKNGTDGN LKIAIDAIGA VSHPHHFLSV TKSGHSAIVH TTGNPDCHVI LRGGKEPNYS
     AEHVQAAVEQ LNKAGVTPKL MVDFSHANSH KDYKRQMEVA QDVVAQIKNG EQNIMGVMVE
     SHLVEGRQDK PEVYGQSITD ACIGWDTTEE MLALLAEANK VRV
//
DBGET integrated database retrieval system