ID A0A238JJF3_9RHOB Unreviewed; 978 AA.
AC A0A238JJF3;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Aminomethyltransferase {ECO:0000313|EMBL:SMX30277.1};
DE EC=2.1.2.10 {ECO:0000313|EMBL:SMX30277.1};
GN Name=gcvT_4 {ECO:0000313|EMBL:SMX30277.1};
GN ORFNames=TRP8649_04420 {ECO:0000313|EMBL:SMX30277.1};
OS Pelagimonas phthalicica.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Pelagimonas.
OX NCBI_TaxID=1037362 {ECO:0000313|EMBL:SMX30277.1, ECO:0000313|Proteomes:UP000225972};
RN [1] {ECO:0000313|Proteomes:UP000225972}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CECT 8649 {ECO:0000313|Proteomes:UP000225972};
RA Rodrigo-Torres L., Arahal R. D., Lucena T.;
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the GcvT family.
CC {ECO:0000256|ARBA:ARBA00008609}.
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DR EMBL; FXXP01000003; SMX30277.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A238JJF3; -.
DR OrthoDB; 5287468at2; -.
DR Proteomes; UP000225972; Unassembled WGS sequence.
DR GO; GO:0004047; F:aminomethyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008115; F:sarcosine oxidase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0046653; P:tetrahydrofolate metabolic process; IEA:InterPro.
DR Gene3D; 3.10.20.440; 2Fe-2S iron-sulphur cluster binding domain, sarcosine oxidase, alpha subunit, N-terminal domain; 1.
DR Gene3D; 1.10.10.1100; BFD-like [2Fe-2S]-binding domain; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR042204; 2Fe-2S-bd_N.
DR InterPro; IPR041854; BFD-like_2Fe2S-bd_dom_sf.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR028896; GCST/YgfZ/DmdA.
DR InterPro; IPR013977; GCV_T_C.
DR InterPro; IPR006222; GCV_T_N.
DR InterPro; IPR029043; GcvT/YgfZ_C.
DR InterPro; IPR006277; Sarcosine_oxidase_asu.
DR InterPro; IPR041117; SoxA_A3.
DR InterPro; IPR027266; TrmE/GcvT_dom1.
DR NCBIfam; TIGR01372; soxA; 1.
DR PANTHER; PTHR43757; AMINOMETHYLTRANSFERASE; 1.
DR PANTHER; PTHR43757:SF2; AMINOMETHYLTRANSFERASE, MITOCHONDRIAL; 1.
DR Pfam; PF12831; FAD_oxidored; 1.
DR Pfam; PF13510; Fer2_4; 1.
DR Pfam; PF01571; GCV_T; 1.
DR Pfam; PF08669; GCV_T_C; 1.
DR Pfam; PF17806; SO_alpha_A3; 1.
DR PIRSF; PIRSF037980; SoxA; 1.
DR PRINTS; PR00368; FADPNR.
DR PRINTS; PR00469; PNDRDTASEII.
DR SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF103025; Folate-binding domain; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000313|EMBL:SMX30277.1};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000225972};
KW Transferase {ECO:0000313|EMBL:SMX30277.1}.
FT DOMAIN 495..580
FT /note="SoxA A3"
FT /evidence="ECO:0000259|Pfam:PF17806"
FT DOMAIN 595..858
FT /note="Aminomethyltransferase folate-binding"
FT /evidence="ECO:0000259|Pfam:PF01571"
FT DOMAIN 884..970
FT /note="Glycine cleavage T-protein C-terminal barrel"
FT /evidence="ECO:0000259|Pfam:PF08669"
SQ SEQUENCE 978 AA; 105139 MW; 7218C5FF287C4EDE CRC64;
MRVEGKGRID RGAPLRFTFD GHTHTGFEGD TLASALMADG VRLMGRSFKY HRPRGVTTAG
SEEPNALVTI GSGARQDPNI RATTQELYDG LEARSQNRWP SLGFDVMGIN DLAAPFLGAG
FYYKTFMWPK AFWEKLYEPV IRRAAGIGAL SGEAPGDKHE KAFAFCDVLV IGGGAAGLMA
ALAAARSGAQ VILCEEDRAC GGRLLAEVEE VDGQPGADWA AALEQQLRDM ENVRVMTRCS
VTGAYDQGTY GALERVAHHV GDPKGAPVEC FWRIHAKRAV LCAGALERPI AFRDNDRPGV
MMAGAMRAYL NRWGVVPGKA LAVFGNNDNA HRTARDLQEA GVHVAALIDS RADAPNLAGD
VPYYAGAQVS RAFGRQGLEA IQIRLPNGKV ERLQVQGLGV SGGWNPSVHL SCHMNTRPVW
DDGIAAFVPG KDAVPGMSVA GAARGRFSTA ACLQDGAEAG QVAASALGFV AEVPQVPEAE
DAPYRLRRLW TVPGKGRAWL DFQNDVTVKD VTQAAQENFR SVEHMKRYTT QGMAPDQGKN
SNIGALAVLA DATGRDIPET GTTTYRPPFV PVSIAAIGAG AEGKGYAPER FTTSHDASVS
AKAPMIEAGL WYRPSYVPRD GEKTWRQSCD REVAMVREHV GICDVSTLGK IELQGPDVGQ
FLDFIYVNGF SSLKPGKVRY GLMLREDGTV MDDGTCARLD DNTWLMTTTT AAAGQVMTHL
DWAQQAFCNK LQMRFVSATE QWAQFAVAGP KSRDLLNALL DAPIDDASLP YMGCVSVTVG
GIAARLFRIS FSGEHAYEIA VPARYGASLF DHLVALAEER GGGAYGMEAL NVLRIEKGFV
THAEINGTAT AFDLGYGRMI SPKKDCIGKV MAARPGLVGE GRQQLVGLRP VSAIKEMPAG
AHLFDDGAEP VRENDQGYVT STCFSPTLGE VRALALVRNG RARHGEVLRL VDHLRGVDMR
CEVTDPVAFD PEGGRLRG
//
