ID A0A238KZE2_9RHOB Unreviewed; 978 AA.
AC A0A238KZE2;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Aminomethyltransferase {ECO:0000313|EMBL:SMX47582.1};
DE EC=2.1.2.10 {ECO:0000313|EMBL:SMX47582.1};
GN Name=gcvT_3 {ECO:0000313|EMBL:SMX47582.1};
GN ORFNames=MAA8898_03696 {ECO:0000313|EMBL:SMX47582.1};
OS Maliponia aquimaris.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae; Maliponia.
OX NCBI_TaxID=1673631 {ECO:0000313|EMBL:SMX47582.1, ECO:0000313|Proteomes:UP000207598};
RN [1] {ECO:0000313|EMBL:SMX47582.1, ECO:0000313|Proteomes:UP000207598}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CECT 8898 {ECO:0000313|EMBL:SMX47582.1,
RC ECO:0000313|Proteomes:UP000207598};
RA Song R., Chenine A.L., Ruprecht R.M.;
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the GcvT family.
CC {ECO:0000256|ARBA:ARBA00008609}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FXYF01000011; SMX47582.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A238KZE2; -.
DR OrthoDB; 5287468at2; -.
DR Proteomes; UP000207598; Unassembled WGS sequence.
DR GO; GO:0004047; F:aminomethyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008115; F:sarcosine oxidase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0046653; P:tetrahydrofolate metabolic process; IEA:InterPro.
DR Gene3D; 3.10.20.440; 2Fe-2S iron-sulphur cluster binding domain, sarcosine oxidase, alpha subunit, N-terminal domain; 1.
DR Gene3D; 1.10.10.1100; BFD-like [2Fe-2S]-binding domain; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR042204; 2Fe-2S-bd_N.
DR InterPro; IPR041854; BFD-like_2Fe2S-bd_dom_sf.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR028896; GCST/YgfZ/DmdA.
DR InterPro; IPR013977; GCV_T_C.
DR InterPro; IPR006222; GCV_T_N.
DR InterPro; IPR029043; GcvT/YgfZ_C.
DR InterPro; IPR006277; Sarcosine_oxidase_asu.
DR InterPro; IPR041117; SoxA_A3.
DR InterPro; IPR027266; TrmE/GcvT_dom1.
DR NCBIfam; TIGR01372; soxA; 1.
DR PANTHER; PTHR43757; AMINOMETHYLTRANSFERASE; 1.
DR PANTHER; PTHR43757:SF2; AMINOMETHYLTRANSFERASE, MITOCHONDRIAL; 1.
DR Pfam; PF12831; FAD_oxidored; 1.
DR Pfam; PF13510; Fer2_4; 1.
DR Pfam; PF01571; GCV_T; 1.
DR Pfam; PF08669; GCV_T_C; 1.
DR Pfam; PF17806; SO_alpha_A3; 1.
DR PRINTS; PR00368; FADPNR.
DR PRINTS; PR00469; PNDRDTASEII.
DR SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 2.
DR SUPFAM; SSF103025; Folate-binding domain; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000313|EMBL:SMX47582.1};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000207598};
KW Transferase {ECO:0000313|EMBL:SMX47582.1}.
FT DOMAIN 495..580
FT /note="SoxA A3"
FT /evidence="ECO:0000259|Pfam:PF17806"
FT DOMAIN 595..857
FT /note="Aminomethyltransferase folate-binding"
FT /evidence="ECO:0000259|Pfam:PF01571"
FT DOMAIN 884..970
FT /note="Glycine cleavage T-protein C-terminal barrel"
FT /evidence="ECO:0000259|Pfam:PF08669"
SQ SEQUENCE 978 AA; 104408 MW; 519D4337D36B63A7 CRC64;
MRIDGKGRVD RAAPLRFSFD GKPYTGFAGD TLASALIGAG ERLIGRSFKY HRPRGVLTAG
SEEPNGLVTV MTAKDADPNA RATVQELYEG LTAISQNRWP SLNFDVMGVN DLAAPFFGAG
FYYKTFMWPK SFWEKLYEPM IRKAAGLGAL SGKHNPDRYE KAYAFCDVLV IGGGPAGIMA
AHAAAQAGAD VILCCEDNVF GGRLQAEEET VDGQPGHAWA LGMVAELATL ENVRVMPRTT
VTGAYDGGTY GALERVSQHL ATPGDAPVEC FWRIAAKRAV LCAGALERHI AFRDNDRPGV
MMAGGLRAYM NRWGVVPGRR VAVFGNNDDA HRTARDAAAA GLSVVALVDS RHDATNLAGD
VPFYPGWQVT RAHGAKGLEA IDLIGPQGAY RRLAVDALGV SGGWNPSVHL TCHLNGRPVW
DDGLAAFVPK PGAVPGMTVA GAVRGTFSTA GCLREGAEAG LAAAAELGFA GEMPVIPEAE
NVAYRVRPLW AVPGKGRAWL DFQNDVTVKD VKQAATENYR SVEHMKRYTT QGMATDQGKS
SNVAALAVLA DATGRGIPET GTTTFRPPYV PVSIAAMGAG SQGKGFAPQR FTTSHDFSVA
RGAPMIEAGL LYRPSDFPRA GGKTWRDSCD REVKMVREAV GVCDVSTLGK IDLQGPDVGA
FLDLVYTNVF STLKPGRVRY GLMLREDGHV MDDGTTARLS DSQWVMTTTT AAAGQVMKHL
DWVKQAYCRD MDLRFVSVTE QWAQFAVAGP KARELLNGLL ETPVEDAGFP YMACGPVSVG
GVAARLFRIS FSGEHAYEIA VPARFGASLF EALVARAEGL GGGAYGMEAL NVMRIEKGHI
THAEIHGRTT AFDIGFARMI SARKDCIGKA LAARPGMVED SREQLVGLRP VTPGSLLTAG
AHLFDKGAEA VRVNDQGYVT SVCFSPTLNT ALGLGFLKNG RARHGEEIRL VDHVRGKEVL
CVVGDPVAFD PEGGRLRG
//
