ID   A0A238LAG5_9RHOB        Unreviewed;      1251 AA.
AC   A0A238LAG5;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   24-JAN-2024, entry version 19.
DE   SubName: Full=Poly(Beta-D-mannuronate) C5 epimerase 1 {ECO:0000313|EMBL:SMY06553.1};
DE            EC=5.1.3.- {ECO:0000313|EMBL:SMY06553.1};
GN   Name=algE1 {ECO:0000313|EMBL:SMY06553.1};
GN   ORFNames=LOM8899_00680 {ECO:0000313|EMBL:SMY06553.1};
OS   Flavimaricola marinus.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Paracoccaceae; Flavimaricola.
OX   NCBI_TaxID=1819565 {ECO:0000313|EMBL:SMY06553.1, ECO:0000313|Proteomes:UP000201613};
RN   [1] {ECO:0000313|EMBL:SMY06553.1, ECO:0000313|Proteomes:UP000201613}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CECT 8899 {ECO:0000313|EMBL:SMY06553.1,
RC   ECO:0000313|Proteomes:UP000201613};
RA   Song R., Chenine A.L., Ruprecht R.M.;
RL   Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
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DR   EMBL; FXZK01000001; SMY06553.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A238LAG5; -.
DR   OrthoDB; 8479154at2; -.
DR   Proteomes; UP000201613; Unassembled WGS sequence.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR   Gene3D; 2.150.10.10; Serralysin-like metalloprotease, C-terminal; 7.
DR   InterPro; IPR010566; Haemolys_ca-bd.
DR   InterPro; IPR018511; Hemolysin-typ_Ca-bd_CS.
DR   InterPro; IPR001343; Hemolysn_Ca-bd.
DR   InterPro; IPR003995; RTX_toxin_determinant-A.
DR   InterPro; IPR011049; Serralysin-like_metalloprot_C.
DR   PANTHER; PTHR38340; S-LAYER PROTEIN; 1.
DR   PANTHER; PTHR38340:SF1; S-LAYER PROTEIN; 1.
DR   Pfam; PF06594; HCBP_related; 1.
DR   Pfam; PF00353; HemolysinCabind; 10.
DR   PRINTS; PR00313; CABNDNGRPT.
DR   PRINTS; PR01488; RTXTOXINA.
DR   SUPFAM; SSF51120; beta-Roll; 5.
DR   PROSITE; PS00330; HEMOLYSIN_CALCIUM; 7.
PE   4: Predicted;
KW   Isomerase {ECO:0000313|EMBL:SMY06553.1};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000201613};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525};
KW   Toxin {ECO:0000256|ARBA:ARBA00022656};
KW   Virulence {ECO:0000256|ARBA:ARBA00023026}.
FT   DOMAIN          443..474
FT                   /note="Haemolysin-type calcium binding-related"
FT                   /evidence="ECO:0000259|Pfam:PF06594"
SQ   SEQUENCE   1251 AA;  127977 MW;  255923F187B8D8DB CRC64;
     MSDATQSGTE LDDSLTGDDG ANTLLGLAGN DTLIGGNGAD RLDGGDGNDI LDAGSNTQSN
     GTEMLLGRGG DDTYLFSSGT YKATVMTEGS NSGSADSVVF GDMSLGDFDA VTINGTTIVF
     EFVNAYGQNS VVTIQGFGNI ESFVFADGAI LTAGDLALSA GSTGDDTLTA LDTGSVLYGG
     AGADSLIGGI GADSLIGGDG DDQIFGGDGG DTLSGAAGDN VLSGGDGSDS YVASQTGGHA
     LILGETGTSG SADTVIFASG YGTLAQPTLT ADGHLLLVVT GPDGQSNSVE IAAYDAIESY
     VFADGTVIDA AQMLGLIATD GNDTIQGLDR NDTLTGMAGS DRIYGNDGDD VLSGGDGRDF
     LFGGEGDDTL HTSANEYTNI DEYLRGGNGN DTYIISRDTG RVMILGETAS SGNADVVIFS
     GIDFDDITGA SIASNGDLRL TLINAGGDEV RITIRDYQAI ERFEFADGIV LTGETITMLA
     TTDVSASDTS HVDLGALDAF DGHNGLTPIA LGQVQNPDGS DYAFAHSYHV PNGMVHNMVD
     GDVWTSASLT NAIEYVVGDD SAQIISNLNS GGDIFFGNGG DDYAHGGGGA DYLNGGAGND
     TLYGGTYSDM VVGGAGNDLL TGDQMNDLLF GGDGDDTLEG GLALDVLFGG AGNDVIISRS
     DSGEPDVRVD GVDPVVVTDD PSSIDISGAA SNDALFGGSG SDLFVFEFTV GAVADPEVLL
     AGVMDLYTLY DDMGTADVLD DIYTINGELD GAGNPKQIKL TDIPIDWTVI TGLNDDRHDH
     WMDGIGNDVI HDFTVGEDQI VFIGHTVAIE GIEYVDTDGN GVLDTVITIG SDHVMDMGGM
     VTPLAHDNDL LGTVTLIDVQ LSEADLAYSV VDVPVHGHDV MELTGDAMID AYLLTNYTDE
     TGAFLSAQEL IPMFSSFETI GQASSYYSSN LGAINTYGDD VPTALFGSDG ADVMQASDLG
     SYLAGGAGDD ILLGSDTYAI QFGRDFIEGG DGDDLIYGSV QDDFLFGGEG DDTILGGGVM
     EMYASGTTIP VGDEDLIFGG AGNDTLAGGP SMDWIEGGDG DDTLLSASDI YIGNYTSDYV
     QFGGSTFEAD DGAELTRDFR TLDDYLIGGD GADSFVFDVL TSEVDGAVIQ TSFGVDTIYD
     FDASEGDTLS ITVHGASAGS AYAEVSAVLV DGIDSAVINV ISTTSDNLAT TIDPISGDPI
     VETDYTGSVG EILLIGVSAA EAEALLDLAG GFTLSEPALG AAAYYEDILG F
//