ID A0A238UA44_9FLAO Unreviewed; 1080 AA.
AC A0A238UA44;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=Tricorn protease homolog {ECO:0000256|PIRNR:PIRNR036421};
DE EC=3.4.21.- {ECO:0000256|PIRNR:PIRNR036421};
GN ORFNames=TJEJU_2382 {ECO:0000313|EMBL:SNR16067.1};
OS Tenacibaculum jejuense.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Tenacibaculum.
OX NCBI_TaxID=584609 {ECO:0000313|EMBL:SNR16067.1, ECO:0000313|Proteomes:UP000215214};
RN [1] {ECO:0000313|EMBL:SNR16067.1, ECO:0000313|Proteomes:UP000215214}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=type strain: KCTC 22618 {ECO:0000313|Proteomes:UP000215214};
RA Sun Z.S., Albrecht U., Echele G., Lee C.C.;
RL Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Degrades oligopeptides. {ECO:0000256|PIRNR:PIRNR036421}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496,
CC ECO:0000256|PIRNR:PIRNR036421}.
CC -!- SIMILARITY: Belongs to the peptidase S41B family.
CC {ECO:0000256|ARBA:ARBA00008524, ECO:0000256|PIRNR:PIRNR036421}.
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DR EMBL; LT899436; SNR16067.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A238UA44; -.
DR KEGG; tje:TJEJU_2382; -.
DR OrthoDB; 9815657at2; -.
DR Proteomes; UP000215214; Chromosome tjeju.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0008236; F:serine-type peptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-UniRule.
DR CDD; cd07562; Peptidase_S41_TRI; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 3.30.750.44; -; 1.
DR Gene3D; 2.120.10.30; TolB, C-terminal domain; 1.
DR Gene3D; 2.120.10.60; Tricorn protease N-terminal domain; 2.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR011659; PD40.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR005151; Tail-specific_protease.
DR InterPro; IPR028204; Tricorn_C1.
DR InterPro; IPR029414; Tricorn_PDZ.
DR InterPro; IPR012393; Tricorn_protease.
DR PANTHER; PTHR43253; TRICORN PROTEASE HOMOLOG 2-RELATED; 1.
DR PANTHER; PTHR43253:SF1; TRICORN PROTEASE HOMOLOG 2-RELATED; 1.
DR Pfam; PF07676; PD40; 4.
DR Pfam; PF03572; Peptidase_S41; 1.
DR Pfam; PF14684; Tricorn_C1; 1.
DR Pfam; PF14685; Tricorn_PDZ; 1.
DR PIRSF; PIRSF036421; Tricorn_protease; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 1.
DR SUPFAM; SSF82171; DPP6 N-terminal domain-like; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF69304; Tricorn protease N-terminal domain; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|PIRNR:PIRNR036421};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PIRNR:PIRNR036421};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PIRNR:PIRNR036421};
KW Reference proteome {ECO:0000313|Proteomes:UP000215214};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825,
KW ECO:0000256|PIRNR:PIRNR036421}.
FT DOMAIN 708..773
FT /note="Tricorn protease C1"
FT /evidence="ECO:0000259|Pfam:PF14684"
FT DOMAIN 809..864
FT /note="Tricorn protease PDZ"
FT /evidence="ECO:0000259|Pfam:PF14685"
FT DOMAIN 899..1052
FT /note="Tail specific protease"
FT /evidence="ECO:0000259|Pfam:PF03572"
FT REGION 567..588
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 770
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR036421-1"
FT ACT_SITE 987
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR036421-1"
FT ACT_SITE 1043
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR036421-1"
FT SITE 988
FT /note="Transition state stabilizer; via amide nitrogen"
FT /evidence="ECO:0000256|PIRSR:PIRSR036421-3"
SQ SEQUENCE 1080 AA; 123144 MW; 897FD8C58A13EF2D CRC64;
MKYISIIFTL LTFNLFSQER PNWLRHSSIS PDGKAIVFTY KGDLYKVPSA GGNAIQLTFH
KAHDYKAIWS KDSKKIAFAS NRYGNFDIYV MDARGGAAER LTFHSTNEIP FSFSADNKNI
IFGAQRQDHV KHRQYPTGSQ PELYSVPVSS GRVSQLLTVP AEDVQVSKDG KTMLYHDKKG
GENEWRKHHK SSITRDIWSY DTNNKTHKMI TSFEGEDRQP IFSEDEKSMY YLSEKSGTFN
VHKMNLNNPN QDQQITSFKL HPVRFLSMGN GTLSFGYDGE LYTMKEGQKP SKVNVTIRTQ
SIDNSDKFVS INGGVNEMAI SPNGKEIAFI ARGEVFVTSV NESFTKRLTN TPERERFVTW
TPDGKSVVYS SERNGRWSIY KTEKVRKEEP FFFASTLIKE TPLIENKSDN YLPEFSPDGS
KIAFVEGRRT LKVMDLKSKK QVTLLTPKDL FHMRDGDKYY TWSPDSKWLL VGWSKTLSNS
EVLLMAADGS KRVNLTESGY SDYYPKWVNG GKQMLWFSNR NGLKSYATSG QSQTDVYSMF
FTQDAWDQFN LSDEDFKLME AIKAEQKKNK KKDTSKKDKK DDKKDKKKTD KKKEVKLLTF
DWDSMKDRTK RLTIHSSSLG DAVLSKKGDI LYYLARFEGK MNLWSTNLRT KETKMVMRLN
ANFGSLQWDK DMKNLYLLNG GRISKIAPAK KSNKGIKING EMELDTNAER EAMFDHVWLR
TNAIFYHPDF HGINWKQMKK EYKKYLPSIG NSFEFSEMLS EMLGELNVSH AGAGYRNSIY
NADATASLGI FMNYDHKDDG ILIDEIIKDG PLDKSSLNVK AGMIIEKIDG ATIDKNVDVA
KYLNRKARKF VLLDITDPKT KKKQTITIKP ISLGKEGSLL YKRWVKTNEK EVERLSNGKL
GYVHIPGMSD GPYRSIYKDI MGKFFERKGM IIDTRFNGGG DLVADLAMFF TGVPFISYET
EAKVVGGEPT SRWTKPTLTM FNESNYSDGH CYAAGYTDLK IGKTVGMPVP GTCSFAGWEG
LPDGSYWGVV PVSAKDKSGR WMENNQTEPM IKIKNMPGII DKGRDQQLER SVQEMLKDLK
//
