ID   A0A238ULJ7_9ACTN        Unreviewed;       494 AA.
AC   A0A238ULJ7;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   24-JAN-2024, entry version 15.
DE   SubName: Full=Mannitol 2-dehydrogenase {ECO:0000313|EMBL:SNR22918.1};
GN   ORFNames=SAMN06272737_10113 {ECO:0000313|EMBL:SNR22918.1};
OS   Blastococcus mobilis.
OC   Bacteria; Actinomycetota; Actinomycetes; Geodermatophilales;
OC   Geodermatophilaceae; Blastococcus.
OX   NCBI_TaxID=1938746 {ECO:0000313|EMBL:SNR22918.1, ECO:0000313|Proteomes:UP000198403};
RN   [1] {ECO:0000313|EMBL:SNR22918.1, ECO:0000313|Proteomes:UP000198403}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44272 {ECO:0000313|EMBL:SNR22918.1,
RC   ECO:0000313|Proteomes:UP000198403};
RA   Kim H.J., Triplett B.A.;
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FZNO01000001; SNR22918.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A238ULJ7; -.
DR   OrthoDB; 271711at2; -.
DR   Proteomes; UP000198403; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0019594; P:mannitol metabolic process; IEA:InterPro.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR013328; 6PGD_dom2.
DR   InterPro; IPR000669; Mannitol_DH.
DR   InterPro; IPR013118; Mannitol_DH_C.
DR   InterPro; IPR023027; Mannitol_DH_CS.
DR   InterPro; IPR013131; Mannitol_DH_N.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR43362:SF1; MANNITOL DEHYDROGENASE 2-RELATED; 1.
DR   PANTHER; PTHR43362; MANNITOL DEHYDROGENASE DSF1-RELATED; 1.
DR   Pfam; PF01232; Mannitol_dh; 1.
DR   Pfam; PF08125; Mannitol_dh_C; 1.
DR   PRINTS; PR00084; MTLDHDRGNASE.
DR   SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS00974; MANNITOL_DHGENASE; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000198403}.
FT   DOMAIN          31..192
FT                   /note="Mannitol dehydrogenase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF01232"
FT   DOMAIN          225..461
FT                   /note="Mannitol dehydrogenase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08125"
SQ   SEQUENCE   494 AA;  53996 MW;  434194E6E7DB6EF4 CRC64;
     MTTSLLRQTT LATLPQTVRR PTYDRAAVRS GVVHLGVGGF HRSHQAVYFD RLLARGHADW
     GITGVGVLAV DRPLHAALRA QDGLYTLVLK AADGSIEPSV IGSLRDLLLL EEDPEAVLGV
     MAAPATRMVT MTITEGGYST DKTTGRFRLD DALAADLGRP LPRTAFGLLT EALRRRRDAG
     TPPFTVVSCD NVEGNGNLAR QTLIEFARLQ QADGEDGMAD WIAATVAFPN SMVDRITPAT
     TDEDRRRLTA ETGVVDQWPV VAEPYLQWVL EDRFSHARPP LDEVGVQLVE DVRPYELMKL
     RLLNASHQVL SYLGYLAGHR RVDEVLADPV FAELVERYMR VEATPTLPPV PDTDLAEYRR
     SLLERFANPA VSDTLARNCA EGSERIATFL LPVIRDQLSH GGPIDIAVLA VAAWARYAAG
     TDEDGNPIAV VDARLEQLIP LVRSQHEDPL AVLTLEEVFG DLVGDERFRG AYSRSAALLN
     RLGARGAVAH LVTS
//