ID   A0A238V2D8_9ACTN        Unreviewed;       727 AA.
AC   A0A238V2D8;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=ATP-dependent DNA helicase RecG {ECO:0000256|ARBA:ARBA00017846};
DE            EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN   ORFNames=SAMN06264365_101523 {ECO:0000313|EMBL:SNR28234.1};
OS   Actinoplanes regularis.
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Actinoplanes.
OX   NCBI_TaxID=52697 {ECO:0000313|EMBL:SNR28234.1, ECO:0000313|Proteomes:UP000198415};
RN   [1] {ECO:0000313|EMBL:SNR28234.1, ECO:0000313|Proteomes:UP000198415}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 43151 {ECO:0000313|EMBL:SNR28234.1,
RC   ECO:0000313|Proteomes:UP000198415};
RA   Kim H.J., Triplett B.A.;
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the helicase family. RecG subfamily.
CC       {ECO:0000256|ARBA:ARBA00007504}.
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DR   EMBL; FZNR01000001; SNR28234.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A238V2D8; -.
DR   OrthoDB; 9804325at2; -.
DR   Proteomes; UP000198415; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   CDD; cd04488; RecG_wedge_OBF; 1.
DR   Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR047112; RecG/Mfd.
DR   InterPro; IPR045562; RecG_dom3_C.
DR   InterPro; IPR033454; RecG_wedge.
DR   PANTHER; PTHR47964; ATP-DEPENDENT DNA HELICASE HOMOLOG RECG, CHLOROPLASTIC; 1.
DR   PANTHER; PTHR47964:SF1; ATP-DEPENDENT DNA HELICASE HOMOLOG RECG, CHLOROPLASTIC; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF19833; RecG_dom3_C; 1.
DR   Pfam; PF17191; RecG_wedge; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:SNR28234.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198415}.
FT   DOMAIN          284..457
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          480..654
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
FT   REGION          502..526
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   727 AA;  78533 MW;  C083E79B4F40C45F CRC64;
     MTTTDTPLTK VLGAKTAKAL AEHLELDTAG DLIYHFPRRY DQRGEHTDLR RLEVGEQVTV
     LAQVQGIGVK PMRQRSGNLL EVTIGDGSGA TLTCTFFNQA WRERELTRGR WGLFAGKVTD
     FRGKRQLNSP NYQLLKADAT QDEAAEEIEE FAGALIPVYP AAQAVATWTI AKCVRTLLDT
     FEPPADPIPR SVRAGRNLVG IGTALREIHR PSSEAALYSA KHRLKWDEAF AVQVTLAQRR
     TRAAAAPGTA RPRRDDGMLA KFDASLPYEL TEGQRTVGEE IADDLARAHP MHRLLQGEVG
     SGKTLVSVRA MLQVVDAGGQ AALLAPTEVL ATQHFRGIGA QLGALGRAGE LDGDHSGTQL
     TLVTGSLGAA ARRAALAKVA DGTAGIVVGT HALLYEGVDF KDLGLIVVDE QHRFGVEQRD
     ALRAKAARPP HVLVMTATPI PRTVAMTVYG DLETSVLSQL PRGRSPIASH VVPALEKPAY
     LDRAWKRVRE EVQAGHQAYV VCPRIGEGPE DDSSPPSDNE PARRPPLAVT EVLPALQQEY
     LKGLRIEMLH GKMPPDEKDA VMRRFAAGDV DVLVATTVIE VGVDVPNSTV MIIMDADRFG
     VSQLHQLRGR VGRGSAPGIC LLHTEAVEGS AARERLDAVA STTDGFKLSE IDLEQRREGD
     VLGASQSGKH SHLRLLSLLR DEKLIKEARA EAATLVAEDP DLTTHPALAA SVAALVDEDR
     AEYLEKG
//