ID A0A238VM51_9ACTN Unreviewed; 328 AA.
AC A0A238VM51;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=N-(2-amino-2-carboxyethyl)-L-glutamate synthase {ECO:0000256|ARBA:ARBA00016985};
DE EC=2.5.1.140 {ECO:0000256|ARBA:ARBA00012331};
GN ORFNames=SAMN06265355_10268 {ECO:0000313|EMBL:SNR35462.1};
OS Actinomadura mexicana.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Thermomonosporaceae; Actinomadura.
OX NCBI_TaxID=134959 {ECO:0000313|EMBL:SNR35462.1, ECO:0000313|Proteomes:UP000198420};
RN [1] {ECO:0000313|EMBL:SNR35462.1, ECO:0000313|Proteomes:UP000198420}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44485 {ECO:0000313|EMBL:SNR35462.1,
RC ECO:0000313|Proteomes:UP000198420};
RA Kim H.J., Triplett B.A.;
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC -!- PATHWAY: Siderophore biosynthesis. {ECO:0000256|ARBA:ARBA00004924}.
CC -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC -!- SIMILARITY: Belongs to the cysteine synthase/cystathionine beta-
CC synthase family. SbnA subfamily. {ECO:0000256|ARBA:ARBA00008519}.
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DR EMBL; FZNP01000002; SNR35462.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A238VM51; -.
DR Proteomes; UP000198420; Unassembled WGS sequence.
DR GO; GO:0016765; F:transferase activity, transferring alkyl or aryl (other than methyl) groups; IEA:UniProt.
DR GO; GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.
DR CDD; cd01561; CBS_like; 1.
DR Gene3D; 3.40.50.1100; -; 2.
DR InterPro; IPR001216; P-phosphate_BS.
DR InterPro; IPR023927; SbnA.
DR InterPro; IPR001926; TrpB-like_PALP.
DR InterPro; IPR036052; TrpB-like_PALP_sf.
DR NCBIfam; TIGR03945; PLP_SbnA_fam; 1.
DR PANTHER; PTHR10314; CYSTATHIONINE BETA-SYNTHASE; 1.
DR PANTHER; PTHR10314:SF254; N-(2-AMINO-2-CARBOXYETHYL)-L-GLUTAMATE SYNTHASE; 1.
DR Pfam; PF00291; PALP; 1.
DR SUPFAM; SSF53686; Tryptophan synthase beta subunit-like PLP-dependent enzymes; 1.
DR PROSITE; PS00901; CYS_SYNTHASE; 1.
PE 3: Inferred from homology;
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898}.
FT DOMAIN 8..295
FT /note="Tryptophan synthase beta chain-like PALP"
FT /evidence="ECO:0000259|Pfam:PF00291"
FT REGION 309..328
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 328 AA; 35419 MW; FD0A73B154CF1D58 CRC64;
MIHESVLGCI GRTPIVALRR LFDEPGVEVL AKLEMLNPGG SVKDRPARHI IEEGLRDGAI
APDSHLVEST SGNFGIALAM VCRIHGLALT VVVDPNITAT NLDLLRRYGA NVDMVGEGEG
SGGYLEQRLR RVREIVSAVP RSVWINQYAN RLNWQAHAES TGKEILADID GPLDCVVMAV
STTGTIHGVT RALRVAYPRL RAVAVDAVGS VIFGHPPAPR RVPGIGAGRV PELLCRDEID
DVVRVDDEQA VQGCHDLLRS EGILAGGSSG SVVAGLRQLL PRLPRPVRVL TLLPDRGERY
LDLLYADAPA EQRSDRSPPA PRRPLSRS
//
