ID   A0A238VYR3_9FLAO        Unreviewed;      1014 AA.
AC   A0A238VYR3;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=Two-component sensor histidine kinase, contains HisKA and HATPase domains {ECO:0000313|EMBL:SNR39013.1};
GN   ORFNames=SAMN06265371_102219 {ECO:0000313|EMBL:SNR39013.1};
OS   Lutibacter agarilyticus.
OC   Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae; Lutibacter.
OX   NCBI_TaxID=1109740 {ECO:0000313|EMBL:SNR39013.1, ECO:0000313|Proteomes:UP000198384};
RN   [1] {ECO:0000313|EMBL:SNR39013.1, ECO:0000313|Proteomes:UP000198384}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 29150 {ECO:0000313|EMBL:SNR39013.1,
RC   ECO:0000313|Proteomes:UP000198384};
RA   Kim H.J., Triplett B.A.;
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FZNT01000002; SNR39013.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A238VYR3; -.
DR   OrthoDB; 358279at2; -.
DR   Proteomes; UP000198384; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd00146; PKD; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR005467; His_kinase_dom.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR   InterPro; IPR011110; Reg_prop.
DR   InterPro; IPR011495; Sig_transdc_His_kin_sub2_dim/P.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR011123; Y_Y_Y.
DR   PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR   PANTHER; PTHR43065:SF23; SENSOR HISTIDINE KINASE PDTAS-RELATED; 1.
DR   Pfam; PF07568; HisKA_2; 1.
DR   Pfam; PF07494; Reg_prop; 2.
DR   Pfam; PF07495; Y_Y_Y; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   SUPFAM; SSF63829; Calcium-dependent phosphotriesterase; 1.
DR   SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
DR   PROSITE; PS50109; HIS_KIN; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000313|EMBL:SNR39013.1}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198384};
KW   Transferase {ECO:0000313|EMBL:SNR39013.1};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        755..774
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          824..1014
FT                   /note="Histidine kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50109"
SQ   SEQUENCE   1014 AA;  116448 MW;  2E729F6B61EA798C CRC64;
     MNRFVLIYFA IFINCLSSQT IKPIDTLHVN YIGQEHGLLQ LNVKDMALDE LGYLWAGTED
     GLHRFNGYEF KTYLHNPLDS SSIKDDHVRG LLFTKDTLWV ATNSKGILGF VPSENRFFSI
     KKNENIDLNI SYKIMPLDEK ELLFSVKNNL ILFNRPAKNS KIIKLPETTK DSYISAILKI
     DINNYWLANT TGILILNTKT YDVQKTTTLE GENIKCFYKN NNNIYIGTEN GLFIYNILNQ
     QISKTPLTFS INCFNKLQEN QFYIGSDKGL FLYDILEESI TPFVLKINEN KLQEKIDINQ
     IINDEKGNLW FGSDGEGLYH YNSFQKKFNT IKLSLKEYPL MNNISSFQFL KGKDSTLWIG
     TKYGIVKYFH KNKNFKLYAT EGDPLIYAIT KDKNNTIWGG GFTTGLLKYD ANTDSFIKIQ
     NTKNNLPDDD IVDIIPIDNN TLWVATWAGG IHKFDIKNEN FEEVFINGKR INRARTSLID
     SKKNIWLGTD QGVFKISKSG IIQNYNEEGA LDQKLSGNRV FNIKEDYNGN IWIGTNTGLT
     KLDIQQHKTT LFYKQKGLPN DFIYSILIAK NNDIWVSTNY GISVLNTETN KFKNYTTSDG
     LQNNEFNGKA GYKDQHDNFY FGGISGINIF KATNIKENQN IPEIYIESVD LFNEPLQKNE
     LYKNVLAFKS DENVLTFNFS ALNYLNPEKC SYTYMMEGFD NDWRPITNSR NTTYTNLNPG
     KYTFKVKASN DVGVWNDVPA TIAIVIIPPW YQTTLFRFSF VILFLLSGIS FYFYKTTRLK
     RDKLKLEKIV TQRTQEILGK NEALKLAYNK SEKQRDSIKF LMRELTHRVK NNLQIISSLL
     NIQANTSDNK EAIDALKIAK NRILAIAHLE SKMTIEKETI KIDEFIKELS QSIITALSDD
     EKLNFTVIYD LADVYIKKVN TVMIGLILNE LITNTTKYAF DDFKPENKLS ISCKFNKTTL
     RLIISDNGKG YSLQKDVLPK SLGIELVTEM VNQLNATITI NSTKGTENII EIPI
//