ID A0A238WBQ1_9ACTN Unreviewed; 360 AA.
AC A0A238WBQ1;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=Galactose-1-phosphate uridylyltransferase {ECO:0000256|ARBA:ARBA00016340};
GN ORFNames=SAMN06272737_10766 {ECO:0000313|EMBL:SNR43714.1};
OS Blastococcus mobilis.
OC Bacteria; Actinomycetota; Actinomycetes; Geodermatophilales;
OC Geodermatophilaceae; Blastococcus.
OX NCBI_TaxID=1938746 {ECO:0000313|EMBL:SNR43714.1, ECO:0000313|Proteomes:UP000198403};
RN [1] {ECO:0000313|EMBL:SNR43714.1, ECO:0000313|Proteomes:UP000198403}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44272 {ECO:0000313|EMBL:SNR43714.1,
RC ECO:0000313|Proteomes:UP000198403};
RA Kim H.J., Triplett B.A.;
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: Belongs to the galactose-1-phosphate uridylyltransferase
CC type 1 family. {ECO:0000256|ARBA:ARBA00010951}.
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DR EMBL; FZNO01000007; SNR43714.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A238WBQ1; -.
DR OrthoDB; 9769064at2; -.
DR UniPathway; UPA00214; -.
DR Proteomes; UP000198403; Unassembled WGS sequence.
DR GO; GO:0008108; F:UDP-glucose:hexose-1-phosphate uridylyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0033499; P:galactose catabolic process via UDP-galactose; IEA:InterPro.
DR Gene3D; 3.30.428.10; HIT-like; 2.
DR InterPro; IPR001937; GalP_UDPtransf1.
DR InterPro; IPR005850; GalP_Utransf_C.
DR InterPro; IPR005849; GalP_Utransf_N.
DR InterPro; IPR036265; HIT-like_sf.
DR NCBIfam; TIGR00209; galT_1; 1.
DR PANTHER; PTHR11943; GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE; 1.
DR PANTHER; PTHR11943:SF1; GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE; 1.
DR Pfam; PF02744; GalP_UDP_tr_C; 1.
DR Pfam; PF01087; GalP_UDP_transf; 1.
DR PIRSF; PIRSF000808; GalT; 1.
DR SUPFAM; SSF54197; HIT-like; 2.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695,
KW ECO:0000313|EMBL:SNR43714.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000198403};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:SNR43714.1};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 38..197
FT /note="Galactose-1-phosphate uridyl transferase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01087"
FT DOMAIN 213..316
FT /note="Galactose-1-phosphate uridyl transferase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02744"
FT ACT_SITE 188
FT /note="Tele-UMP-histidine intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000808-1"
SQ SEQUENCE 360 AA; 40297 MW; 4318A47E8CB82C5A CRC64;
MIRTSRRLAD GREILYFDRE PTSRDAVDLR DLPAVATRSQ LRYDALSGEW VVVASHRQTR
TFLPPADECP LDPSRPGRPT EVPESDYQVV VFENRFPSLS TGVDRDVPTE APGNPLAELR
PGFGRAEVVL FTSDHDRVFA DLGADRARLV VDVWAERTAE LSALDGVEQV FCFENHGEEI
GVTLSHPHGQ IYAYPFVTPR VEKVLGSVQR HRAATGGDLF AEVVAAEAAG PRVVVANEHW
TAFVPAAARW PYEVQFFPLR KVPDLPALGD AERDAFVEVY LDVLARFARR FDTPMPYIAS
WNQAPVRHRD DWWLHLQLFS LRRAPGKLKY LAGSESGMGA FITDTNPEDV AEQLRAVVVQ
//
