ID A0A238XPB2_9BACT Unreviewed; 706 AA.
AC A0A238XPB2;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 12.
DE RecName: Full=HD domain-containing protein {ECO:0000259|PROSITE:PS51831};
GN ORFNames=SAMN06265340_101126 {ECO:0000313|EMBL:SNR60381.1};
OS Desulfurobacterium atlanticum.
OC Bacteria; Aquificota; Aquificae; Desulfurobacteriales;
OC Desulfurobacteriaceae; Desulfurobacterium.
OX NCBI_TaxID=240169 {ECO:0000313|EMBL:SNR60381.1, ECO:0000313|Proteomes:UP000198405};
RN [1] {ECO:0000313|EMBL:SNR60381.1, ECO:0000313|Proteomes:UP000198405}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15668 {ECO:0000313|EMBL:SNR60381.1,
RC ECO:0000313|Proteomes:UP000198405};
RA Kim H.J., Triplett B.A.;
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FZOB01000001; SNR60381.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A238XPB2; -.
DR Proteomes; UP000198405; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00077; HDc; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR006674; HD_domain.
DR InterPro; IPR006675; HDIG_dom.
DR InterPro; IPR011624; Metal-dep_PHydrolase_7TM_extra.
DR InterPro; IPR011621; Metal-dep_PHydrolase_7TM_intra.
DR NCBIfam; TIGR00277; HDIG; 1.
DR PANTHER; PTHR36442; CYCLIC-DI-AMP PHOSPHODIESTERASE PGPH; 1.
DR PANTHER; PTHR36442:SF1; CYCLIC-DI-AMP PHOSPHODIESTERASE PGPH; 1.
DR Pfam; PF07698; 7TM-7TMR_HD; 1.
DR Pfam; PF07697; 7TMR-HDED; 1.
DR Pfam; PF01966; HD; 1.
DR SMART; SM00471; HDc; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR PROSITE; PS51831; HD; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..42
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 270..291
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 303..325
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 337..354
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 366..391
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 403..424
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 436..460
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 493..635
FT /note="HD"
FT /evidence="ECO:0000259|PROSITE:PS51831"
SQ SEQUENCE 706 AA; 79658 MW; 1C860D5C450FC349 CRC64;
MRKMKSKGIK EFLIELTEKV SLPILAVVLS AFITFIMLPV GFGSIPKLKV KEISPVDIRS
PANLIVEDKK ATEKKIETAL KQLKPVFKVD PQAFSSIKET VLKKFYTSQA ENSTDKTGSS
VKPEFIIDLL ERYYSVGVID DKTFEKFKGK TVKVVNPLTS TSTEKNISSF YTVSKVKKRI
SAELRNFYGR KKGKEIYTFI EPLIVPNIKY SEKATFKARE RILKQVKPVL YEIKKGELIV
KKGSRLTEED VQKINAIRKL KDSNKTANRY ISIFLISLIM FYIVYRLYFI VSPTAAKDVK
NITFSYVVIT LDVFLIRFFT FLAKLMAEAM NIPVKEGLIY IPVITSVIFV SLFLNKKVAF
IHSIPVSILP SFILSKPHFF IIPVVAGSVF SCLDSRSYQD RNVIYKSSFL AGLGIAVFQI
LLLIYSNGLV FKREFIFYPI LAILGSLIAS VIVIGLLPLF GSIFKFTTDM VYMELINLNH
PLLRKLVLKA PGTYSHSVMV STLAEAAAET IGANSLLAKA GGLFHDIGKL KNPQAFVENQ
QNGINIHETI PPEKSAAILK SHVEYGVELG KKYNLPQPII DIIKQHHGTK LMKYFYAKAK
EQKKEIDEKV FRYPGPKPQF KEAGIVMLAD TIEAAVKSVR DKKDVDIDKL VHKLIMEDVE
DGQLNQSGLS LKEIALIEKV FKKVLSGIYH NRVEYPDNSS EKAQNQ
//
