ID   A0A238XPB6_9FLAO        Unreviewed;       541 AA.
AC   A0A238XPB6;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   24-JAN-2024, entry version 14.
DE   SubName: Full=Alanine or glycine:cation symporter, AGCS family {ECO:0000313|EMBL:SNR60428.1};
GN   ORFNames=SAMN04488111_1973 {ECO:0000313|EMBL:SNR60428.1};
OS   Lutibacter flavus.
OC   Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae; Lutibacter.
OX   NCBI_TaxID=691689 {ECO:0000313|EMBL:SNR60428.1, ECO:0000313|Proteomes:UP000198412};
RN   [1] {ECO:0000313|Proteomes:UP000198412}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 27993 {ECO:0000313|Proteomes:UP000198412};
RA   Varghese N., Submissions S.;
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363064};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU363064}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the alanine or glycine:cation symporter (AGCS)
CC       (TC 2.A.25) family. {ECO:0000256|ARBA:ARBA00009261,
CC       ECO:0000256|RuleBase:RU363064}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FZNX01000003; SNR60428.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A238XPB6; -.
DR   OrthoDB; 9804874at2; -.
DR   Proteomes; UP000198412; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005283; F:amino acid:sodium symporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR   InterPro; IPR001463; Na/Ala_symport.
DR   NCBIfam; TIGR00835; agcS; 1.
DR   PANTHER; PTHR30330; AGSS FAMILY TRANSPORTER, SODIUM-ALANINE; 1.
DR   PANTHER; PTHR30330:SF3; TRANSCRIPTIONAL REGULATOR, LRP FAMILY-RELATED; 1.
DR   Pfam; PF01235; Na_Ala_symp; 1.
DR   PRINTS; PR00175; NAALASMPORT.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|RuleBase:RU363064};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363064};
KW   Signal {ECO:0000256|SAM:SignalP}; Symport {ECO:0000256|RuleBase:RU363064};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU363064};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU363064};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363064}.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           20..541
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5012444131"
FT   TRANSMEM        57..77
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        213..234
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        254..275
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        287..307
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        313..337
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        370..394
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        437..459
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        480..498
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        504..520
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
SQ   SEQUENCE   541 AA;  57613 MW;  4E6EBACD73166DEC CRC64;
     MSKKLLSLLL LVVPFLTFAQ ESAEKGLDER INEGFMPFAT WWEGFVLTTV PIAGNNVPLV
     VLLLVIGATF FTIYFGFPAV TKFRLAINTV RGKYDEIDHH GVEKADLNIV DGDLVDTIGD
     ESKDGEVSHF QALATAVSGT VGLGNIAGVA VAIAVGGPGA TFWMVVCGLI GMSTKFVECT
     LGVKYRDVGE DGTVYGGPMY YLKRGLEAQN KAILGKILAV MFAVLCVGAS FGGGNAFQSN
     QAAVQIESML GLEGGASGFI IGVIMAILVG IVIIGGIKRI AKITEKIVPF MAGIYIIASL
     VIIFANIKYV GDAFSMIFSG AFTPEAGLGG VLGVLIVGFQ RAAFSNEAGA GSAAIAHSAV
     KTKYPASEGV VALLEPFIDT VVICTMTALV IIFFNMDAGA FDYGNSVNSA VLLNETQQYI
     GGVDLTSMAF DSVIPGFSYV LTIAIILFAF STMISWSYYG LQSWKYLFGR GKSADLVYKF
     LFLIFVVIGA SATLDAVIKF SDAMILALVF PNMIGLLLLF PRVREEMETY IEAIKTVTVK
     K
//