ID   A0A238XPK9_9PROT        Unreviewed;       499 AA.
AC   A0A238XPK9;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   RecName: Full=Exopolyphosphatase {ECO:0000256|ARBA:ARBA00020416};
DE            EC=3.6.1.11 {ECO:0000256|ARBA:ARBA00012451};
GN   ORFNames=SAMN05192560_0068 {ECO:0000313|EMBL:SNR60518.1};
OS   Methylobacillus rhizosphaerae.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC   Methylophilaceae; Methylobacillus.
OX   NCBI_TaxID=551994 {ECO:0000313|EMBL:SNR60518.1, ECO:0000313|Proteomes:UP000198305};
RN   [1] {ECO:0000313|EMBL:SNR60518.1, ECO:0000313|Proteomes:UP000198305}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ca-68 {ECO:0000313|EMBL:SNR60518.1,
RC   ECO:0000313|Proteomes:UP000198305};
RA   Kim H.J., Triplett B.A.;
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=[phosphate](n) + H2O = [phosphate](n-1) + H(+) + phosphate;
CC         Xref=Rhea:RHEA:21528, Rhea:RHEA-COMP:9859, Rhea:RHEA-COMP:14279,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:16838,
CC         ChEBI:CHEBI:43474; EC=3.6.1.11;
CC         Evidence={ECO:0000256|ARBA:ARBA00000209};
CC   -!- SIMILARITY: Belongs to the GppA/Ppx family.
CC       {ECO:0000256|ARBA:ARBA00007125}.
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DR   EMBL; FZOA01000001; SNR60518.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A238XPK9; -.
DR   OrthoDB; 9793035at2; -.
DR   Proteomes; UP000198305; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004309; F:exopolyphosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006793; P:phosphorus metabolic process; IEA:InterPro.
DR   Gene3D; 3.30.420.40; -; 1.
DR   Gene3D; 3.30.420.150; Exopolyphosphatase. Domain 2; 1.
DR   Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR022371; Exopolyphosphatase.
DR   InterPro; IPR048950; Ppx_GppA_C.
DR   InterPro; IPR003695; Ppx_GppA_N.
DR   InterPro; IPR030673; PyroPPase_GppA_Ppx.
DR   NCBIfam; TIGR03706; exo_poly_only; 1.
DR   PANTHER; PTHR30005; EXOPOLYPHOSPHATASE; 1.
DR   PANTHER; PTHR30005:SF0; RETROGRADE REGULATION PROTEIN 2; 1.
DR   Pfam; PF02541; Ppx-GppA; 1.
DR   Pfam; PF21447; Ppx-GppA_III; 1.
DR   PIRSF; PIRSF001267; Pyrophosphatase_GppA_Ppx; 1.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR   SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
PE   3: Inferred from homology;
FT   DOMAIN          26..306
FT                   /note="Ppx/GppA phosphatase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02541"
FT   DOMAIN          313..484
FT                   /note="Ppx/GppA phosphatase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF21447"
SQ   SEQUENCE   499 AA;  55122 MW;  D702A48226A521BA CRC64;
     MATRPSEFPE IAAVDLGSNS FRLQLARVTD GHLLFHDSLR ETVRLGAGLD EKNNLSTEAQ
     QRAIDCLKRF GERLRGLPPQ AVRAVATNTF RVARNAPNFM REAQEALGFP IEIIAGREEA
     RMIFVGVSHS LPPATHKRLV IDIGGGSTEF IIGQSLEPIA MESLYMGCVS YSLRYFPDGK
     ITEAGMRRAR IAAAAEIQGI RKHFLSEGWD EAVGSSGTAK ALGEISRLSG LGEGEITRDG
     LEFISQQILQ AGSIRKINLP GISADRAAVL PGGVAVMMAA FDALKIERMT AANSALREGV
     LYELLGRLHD QDVRETTVSS FMRRYHVEPD QAERVRELAL DLLAQSRSRL QHMDADTAAQ
     YLTWAASLHE IGISIAHAGY HKHSAYIVEN ADMPGFSNIE QETLGLLVKA HRRSLGKLEA
     SLIGSHDRLL LVLILRLAVL FHRNRQPDHY PQPELLITKS GYQLNIEADW LKENPLTEAE
     LLNEVTYWKE IGLTLELGV
//