ID   A0A238Y1M4_9PROT        Unreviewed;       352 AA.
AC   A0A238Y1M4;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=Uncharacterized zinc-type alcohol dehydrogenase-like protein {ECO:0000313|EMBL:SNR64880.1};
GN   ORFNames=SAMN05192560_0357 {ECO:0000313|EMBL:SNR64880.1};
OS   Methylobacillus rhizosphaerae.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC   Methylophilaceae; Methylobacillus.
OX   NCBI_TaxID=551994 {ECO:0000313|EMBL:SNR64880.1, ECO:0000313|Proteomes:UP000198305};
RN   [1] {ECO:0000313|EMBL:SNR64880.1, ECO:0000313|Proteomes:UP000198305}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ca-68 {ECO:0000313|EMBL:SNR64880.1,
RC   ECO:0000313|Proteomes:UP000198305};
RA   Kim H.J., Triplett B.A.;
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947,
CC         ECO:0000256|RuleBase:RU361277};
CC   -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC       family. {ECO:0000256|ARBA:ARBA00008072, ECO:0000256|RuleBase:RU361277}.
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DR   EMBL; FZOA01000001; SNR64880.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A238Y1M4; -.
DR   OrthoDB; 9771084at2; -.
DR   Proteomes; UP000198305; Unassembled WGS sequence.
DR   GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd05283; CAD1; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR013154; ADH-like_N.
DR   InterPro; IPR002328; ADH_Zn_CS.
DR   InterPro; IPR047109; CAD-like.
DR   InterPro; IPR029752; D-isomer_DH_CS1.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   PANTHER; PTHR42683; ALDEHYDE REDUCTASE; 1.
DR   PANTHER; PTHR42683:SF85; CINNAMYL ALCOHOL DEHYDROGENASE 6-RELATED; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS00059; ADH_ZINC; 1.
DR   PROSITE; PS00065; D_2_HYDROXYACID_DH_1; 1.
PE   3: Inferred from homology;
KW   Metal-binding {ECO:0000256|RuleBase:RU361277};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Zinc {ECO:0000256|RuleBase:RU361277}.
FT   DOMAIN          13..343
FT                   /note="Enoyl reductase (ER)"
FT                   /evidence="ECO:0000259|SMART:SM00829"
SQ   SEQUENCE   352 AA;  38347 MW;  85F613C090F4A6B5 CRC64;
     MAKAISYAAH DPKSPLAPFS FERREVGNTD VQIEILFCGV CHSDLHQVRD EWANSTFPLV
     PGHEIVGRVT QVGSNVKHFK VGDLAGVGCM VDSCGTCPDC AEGLEQYCNH SVFTYNSPDK
     HMPGQATYGG YSNQIVVDER FTLKISDKLD LAATAPLLCA GITTYSPLRH WKVGPGQKVG
     IVGLGGLGHM GVKFAKAFGA HTVLFTTSAN KVEDAKRLGA DEVVISKDSE QMQQHLQSFD
     FILNTVAAPH NLDQFMALLK RDGSMCLVGV PDSPHPSPNI ANLIFKRRQL AGSLIGGIRE
     TQEMLDFCAE HNITSDVELI AIQDINTAFD RMLKSDVKYR FVIDIASLKQ AA
//