ID A0A238Y8V7_9ACTN Unreviewed; 451 AA.
AC A0A238Y8V7;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=SAMN06265355_105324 {ECO:0000313|EMBL:SNR67171.1};
OS Actinomadura mexicana.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Thermomonosporaceae; Actinomadura.
OX NCBI_TaxID=134959 {ECO:0000313|EMBL:SNR67171.1, ECO:0000313|Proteomes:UP000198420};
RN [1] {ECO:0000313|EMBL:SNR67171.1, ECO:0000313|Proteomes:UP000198420}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44485 {ECO:0000313|EMBL:SNR67171.1,
RC ECO:0000313|Proteomes:UP000198420};
RA Kim H.J., Triplett B.A.;
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; FZNP01000005; SNR67171.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A238Y8V7; -.
DR OrthoDB; 2514702at2; -.
DR Proteomes; UP000198420; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR010559; Sig_transdc_His_kin_internal.
DR PANTHER; PTHR34220; SENSOR HISTIDINE KINASE YPDA; 1.
DR PANTHER; PTHR34220:SF7; SENSOR HISTIDINE KINASE YPDA; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF06580; His_kinase; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:SNR67171.1};
KW Transferase {ECO:0000313|EMBL:SNR67171.1}.
FT DOMAIN 325..445
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT REGION 87..123
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 451 AA; 47839 MW; EAAE626D4BD7EFC3 CRC64;
MDLPSVTDVV VCAAAAGASG VWAPRRWCLL PRRGPADPAE AAALAALHLI AHAAPPLRAG
LTGDAARRAT RLLRSLLGAE AVAIVAVRPP DDPDDPDDPD HPDDFDGPDG PDKPGDGTRD
APRLLAWDGA GRGAHAGEAV AHALPVLTSG RPRVITPEPL ACGDPHCGVR AAMIAPLTVE
GRVEGTLAAY WPSPSTARVR AVGEAARLVT GQLELAGLDS VRVRLAEAEM RALRAQISPH
FVYNSLTTIA SFVRTDPERA RGLLLDFADF ARYSFRNPRD FTTLADELRS IDRYLLLERA
RFGERLRCEV EVAPEVLPVA VPFLALQPLV ENAVRHGMAG GRRAFHISIV ARDSGAEAAI
SIEDDGIGMD PERLEEILSA PLGRPGPTGW GSVATHDRSE GGGPGIGLAN VDARMRQVYG
DEYGLTVETA LGAGTKVKLR VPKYRPGVFP D
//
