ID A0A238Z126_9ACTN Unreviewed; 483 AA.
AC A0A238Z126;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Capsular exopolysaccharide family {ECO:0000313|EMBL:SNR77067.1};
GN ORFNames=SAMN06272737_12424 {ECO:0000313|EMBL:SNR77067.1};
OS Blastococcus mobilis.
OC Bacteria; Actinomycetota; Actinomycetes; Geodermatophilales;
OC Geodermatophilaceae; Blastococcus.
OX NCBI_TaxID=1938746 {ECO:0000313|EMBL:SNR77067.1, ECO:0000313|Proteomes:UP000198403};
RN [1] {ECO:0000313|EMBL:SNR77067.1, ECO:0000313|Proteomes:UP000198403}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44272 {ECO:0000313|EMBL:SNR77067.1,
RC ECO:0000313|Proteomes:UP000198403};
RA Kim H.J., Triplett B.A.;
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-
CC [protein]; Xref=Rhea:RHEA:10596, Rhea:RHEA-COMP:10136, Rhea:RHEA-
CC COMP:10137, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:46858,
CC ChEBI:CHEBI:82620, ChEBI:CHEBI:456216;
CC Evidence={ECO:0000256|ARBA:ARBA00001074};
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004429}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the etk/wzc family.
CC {ECO:0000256|ARBA:ARBA00008883}.
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DR EMBL; FZNO01000024; SNR77067.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A238Z126; -.
DR OrthoDB; 9812433at2; -.
DR Proteomes; UP000198403; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0045226; P:extracellular polysaccharide biosynthetic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd05387; BY-kinase; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR025669; AAA_dom.
DR InterPro; IPR003856; LPS_length_determ_N_term.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005702; Wzc-like_C.
DR NCBIfam; TIGR01007; eps_fam; 1.
DR PANTHER; PTHR32309; TYROSINE-PROTEIN KINASE; 1.
DR PANTHER; PTHR32309:SF13; TYROSINE-PROTEIN KINASE ETK-RELATED; 1.
DR Pfam; PF13614; AAA_31; 1.
DR Pfam; PF02706; Wzz; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000198403};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Tyrosine-protein kinase {ECO:0000256|ARBA:ARBA00023137}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 7..89
FT /note="Polysaccharide chain length determinant N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02706"
FT DOMAIN 272..401
FT /note="AAA"
FT /evidence="ECO:0000259|Pfam:PF13614"
FT REGION 143..173
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 439..483
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 143..165
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 483 AA; 50717 MW; 2BA499E3F44D34C2 CRC64;
MQGNVTLRSL RDHSYFIVLG VLLGLGAAGL LTWTTERTYT SSTQLFVGAV GATDTADAYE
GNLFSQERVA SYAQILTSPD LAERVVDELG LDLTAGELAA KVTAAPVPET VVLEVKVTDT
SAERAQAIAT SLGRQFASRV TELETPAGAS SSTVAVSTIQ TPDFNPEPAS PDVPGTLGRG
AAIGLVLGTG VALLRTRTDR AVRRDDDVEE AAGAHVVGRV LEQHRWARTR LPADVFGQSP
AAEAYRALRV NLRHLDGRRR PQAVVVTGPL PGAGASTVAV NLSASLAASG QRVLLIDGDL
RRPRVTHCLG LPDGPGLTDV LTGSAELHDV VRPWRGGRLS VLGAGPLPSD PEALLGSARM
RSLLDVLRDQ YDQVILDAPP LLSVVDAAVL SAVADSCLLV ARYGRTRREH LAEAAAMVTR
VRVPSLGVVL NRVPRRAAVG SPGARGYRAE GHRRTTETMV AGSSADPDAR PGAGAPDRLP
PHE
//
