ID   A0A239AJP4_9ACTN        Unreviewed;       589 AA.
AC   A0A239AJP4;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Drug resistance transporter, EmrB/QacA subfamily {ECO:0000313|EMBL:SNR95264.1};
GN   ORFNames=SAMN06893096_10118 {ECO:0000313|EMBL:SNR95264.1};
OS   Geodermatophilus pulveris.
OC   Bacteria; Actinomycetota; Actinomycetes; Geodermatophilales;
OC   Geodermatophilaceae; Geodermatophilus.
OX   NCBI_TaxID=1564159 {ECO:0000313|EMBL:SNR95264.1, ECO:0000313|Proteomes:UP000198373};
RN   [1] {ECO:0000313|EMBL:SNR95264.1, ECO:0000313|Proteomes:UP000198373}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 46839 {ECO:0000313|EMBL:SNR95264.1,
RC   ECO:0000313|Proteomes:UP000198373};
RA   Kim H.J., Triplett B.A.;
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; FZOO01000001; SNR95264.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A239AJP4; -.
DR   OrthoDB; 7375466at2; -.
DR   Proteomes; UP000198373; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   CDD; cd17502; MFS_Azr1_MDR_like; 1.
DR   Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR   InterPro; IPR004638; EmrB-like.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   NCBIfam; TIGR00711; efflux_EmrB; 1.
DR   PANTHER; PTHR23501; MAJOR FACILITATOR SUPERFAMILY; 1.
DR   PANTHER; PTHR23501:SF191; VACUOLAR BASIC AMINO ACID TRANSPORTER 4; 1.
DR   Pfam; PF07690; MFS_1; 1.
DR   PRINTS; PR01036; TCRTETB.
DR   SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        33..58
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        70..89
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        101..124
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        130..150
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        162..183
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        195..215
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        227..245
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        257..275
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        295..316
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        328..349
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        361..381
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        387..410
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        511..530
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          36..535
FT                   /note="Major facilitator superfamily (MFS) profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50850"
FT   REGION          546..589
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   589 AA;  61742 MW;  AEEA9005B7B65E16 CRC64;
     MSHSTSTPAV DRGAAAAAAR EPDEHGVFSH RQILTIVAGL MVAMFLAALD QTIVSTAIRT
     IADDLQGYDL QVWATTAFLI TSTISTPLYG KLSDIYGRRP FYLFAIALFV VGSVLCGLAD
     SMYQLAAYRA VQGAGAGGLM SLALAIIGDI VPPRQRSRYQ GYFMAVFGMS SVLGPVIGGF
     FAGQGSLFGL DGWRWIFLVN VPLGALAFAA VYRVLHLPHV RREHRVDWPG ALALVTFVVP
     LLVIAEQGRL WGWTSGRALL CYAVGALGFA LFVAIERAYR EEALLPLGLF RNRSFTVATL
     GSVVVGAAMF GGLLLLPQYL QIVQGSSATV AGLQMIPLVL GIMIGAMSSG LRISRTGRYR
     VFPLLGTALM TAALLSLSFV VGAETSVWVL VPFMVALGVG LGFNFQPAVL AVQNAVPPSQ
     LGVATSSVTF FRQMGATVGT AALLSVLFSR LPVEIEESVA AAAAGDPRVA QAAQSGQLPV
     GEALSDTSFI QELPGYLALP FKVGFSDSLD LVFLIAAAAA AVGFLVFLFL PQLELSDKSG
     IQAAREAAEQ TAGAPDAEDA DEQVRQAVGA AAPTSTAPPA GRPGDAATR
//