ID A0A239AUU8_9FLAO Unreviewed; 378 AA.
AC A0A239AUU8;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE RecName: Full=beta-lactamase {ECO:0000256|ARBA:ARBA00012865};
DE EC=3.5.2.6 {ECO:0000256|ARBA:ARBA00012865};
GN ORFNames=SAMN06265376_105117 {ECO:0000313|EMBL:SNR98743.1};
OS Dokdonia pacifica.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Dokdonia.
OX NCBI_TaxID=1627892 {ECO:0000313|EMBL:SNR98743.1, ECO:0000313|Proteomes:UP000198379};
RN [1] {ECO:0000313|EMBL:SNR98743.1, ECO:0000313|Proteomes:UP000198379}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 25597 {ECO:0000313|EMBL:SNR98743.1,
RC ECO:0000313|Proteomes:UP000198379};
RA Kim H.J., Triplett B.A.;
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a beta-lactam + H2O = a substituted beta-amino acid;
CC Xref=Rhea:RHEA:20401, ChEBI:CHEBI:15377, ChEBI:CHEBI:35627,
CC ChEBI:CHEBI:140347; EC=3.5.2.6;
CC Evidence={ECO:0000256|ARBA:ARBA00001526};
CC -!- SIMILARITY: Belongs to the class-A beta-lactamase family.
CC {ECO:0000256|ARBA:ARBA00009009}.
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DR EMBL; FZNY01000005; SNR98743.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A239AUU8; -.
DR OrthoDB; 1884322at2; -.
DR Proteomes; UP000198379; Unassembled WGS sequence.
DR GO; GO:0008800; F:beta-lactamase activity; IEA:InterPro.
DR GO; GO:0030655; P:beta-lactam antibiotic catabolic process; IEA:InterPro.
DR GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR045155; Beta-lactam_cat.
DR InterPro; IPR000871; Beta-lactam_class-A.
DR PANTHER; PTHR35333; BETA-LACTAMASE; 1.
DR PANTHER; PTHR35333:SF3; BETA-LACTAMASE2 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13354; Beta-lactamase2; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Antibiotic resistance {ECO:0000256|ARBA:ARBA00023251};
KW Reference proteome {ECO:0000313|Proteomes:UP000198379}.
FT DOMAIN 65..323
FT /note="Beta-lactamase class A catalytic"
FT /evidence="ECO:0000259|Pfam:PF13354"
SQ SEQUENCE 378 AA; 43790 MW; BCF440CDA04953DC CRC64;
MRISLFMLIA SSLFLGSCTT PIDTVLESSD HPAIQKVMDS LENHEIQILY TQIDTTDKGL
IEFTDYTFQE NRKQYFYPAS TVKLPIALLA AEYVNEHPEL HLDTPYISTR DSILHSVADD
IRQIFAVSDN EAYNRLYDML GRDYINKRLK ELDLSPTRIA HRLSTGNAAI PERGTIKFFP
SYEGEVVALK GLTDQPIKNV SIKNQQKGKG YIKDGNLIQT PFDFTEKNYF PLKSQHTLMK
RFFFEDQFDP DERFDISYTD KVRIQKSMYT LPRNAKYDAE TYDDSYVKFF MYGDSKDTIP
DHIKIYNKVG YAYGTLTETA YVVDEKEEIQ FLLSATILVN ENGIFNDDTY EYDTIGIPFL
AQLGREIYDL EKSRKQEK
//
