ID   A0A239B9P5_9ACTN        Unreviewed;       409 AA.
AC   A0A239B9P5;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   SubName: Full=L-2-hydroxyglutarate oxidase {ECO:0000313|EMBL:SNS04332.1};
GN   ORFNames=SAMN05216252_102467 {ECO:0000313|EMBL:SNS04332.1};
OS   Actinacidiphila glaucinigra.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Actinacidiphila.
OX   NCBI_TaxID=235986 {ECO:0000313|EMBL:SNS04332.1, ECO:0000313|Proteomes:UP000198280};
RN   [1] {ECO:0000313|EMBL:SNS04332.1, ECO:0000313|Proteomes:UP000198280}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 4.1858 {ECO:0000313|EMBL:SNS04332.1,
RC   ECO:0000313|Proteomes:UP000198280};
RA   Kim H.J., Triplett B.A.;
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|ARBA:ARBA00001974};
CC   -!- SIMILARITY: Belongs to the L2HGDH family.
CC       {ECO:0000256|ARBA:ARBA00037941}.
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DR   EMBL; FZOF01000002; SNS04332.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A239B9P5; -.
DR   OrthoDB; 9801699at2; -.
DR   Proteomes; UP000198280; Unassembled WGS sequence.
DR   GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:UniProt.
DR   Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   InterPro; IPR006076; FAD-dep_OxRdtase.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   PANTHER; PTHR43104; L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR43104:SF2; L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR   Pfam; PF01266; DAO; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE   3: Inferred from homology;
KW   FAD {ECO:0000256|ARBA:ARBA00022827};
KW   Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198280}.
FT   DOMAIN          5..401
FT                   /note="FAD dependent oxidoreductase"
FT                   /evidence="ECO:0000259|Pfam:PF01266"
SQ   SEQUENCE   409 AA;  43813 MW;  09003C411F92A487 CRC64;
     MDSADIVVIG AGIVGLATAY AITRTSPGTS VLVLDKEDGP ARHQTGHNSG VIHSGIYYRP
     GSLKARYATQ GAAEMVKFCA GNDIPHDVTG KLIVATEREE LPRLHALVQR GRQNDIPVQE
     LGPAQIAERE PHVRGLAAIH VGTTGVCDFT AVAAALARLT TEGGRGEARI AYGREVRALH
     RDGRSVIVEP HSGPPVRAGA LVNCAGLYCD RVARMAGTTN EDVAGVRIVP FRGEYHELRP
     DRAGLVRGLV YPVPDPAFPF LGVHLTRGVD GSVHVGPNAV PALAREGYRR RTVRPRDLVE
     TAAFPGTWRI ARRHWRYEAG EIRRSLSKRA FVESVQRLLP EVTADDLVPA EAGVRAQAVL
     RDGTLVDDFL IAGDGPFVHV LNAPSPAATA SLPIGREIAR RALAVLGRT
//