ID   A0A239BEL6_9ACTN        Unreviewed;       509 AA.
AC   A0A239BEL6;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=NTF2-like N-terminal transpeptidase domain-containing protein {ECO:0000313|EMBL:SNS06487.1};
GN   ORFNames=SAMN05216276_1003167 {ECO:0000313|EMBL:SNS06487.1};
OS   Streptosporangium subroseum.
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Streptosporangiaceae; Streptosporangium.
OX   NCBI_TaxID=106412 {ECO:0000313|EMBL:SNS06487.1, ECO:0000313|Proteomes:UP000198282};
RN   [1] {ECO:0000313|EMBL:SNS06487.1, ECO:0000313|Proteomes:UP000198282}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 4.2132 {ECO:0000313|EMBL:SNS06487.1,
RC   ECO:0000313|Proteomes:UP000198282};
RA   Kim H.J., Triplett B.A.;
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the transpeptidase family.
CC       {ECO:0000256|ARBA:ARBA00007171}.
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DR   EMBL; FZOD01000003; SNS06487.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A239BEL6; -.
DR   OrthoDB; 5241017at2; -.
DR   Proteomes; UP000198282; Unassembled WGS sequence.
DR   GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR   GO; GO:0046677; P:response to antibiotic; IEA:InterPro.
DR   Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR   InterPro; IPR012338; Beta-lactam/transpept-like.
DR   InterPro; IPR007887; MecA_N.
DR   InterPro; IPR032710; NTF2-like_dom_sf.
DR   InterPro; IPR001460; PCN-bd_Tpept.
DR   PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR   PANTHER; PTHR30627:SF24; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE PBPA; 1.
DR   Pfam; PF05223; MecA_N; 1.
DR   Pfam; PF00905; Transpeptidase; 1.
DR   SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR   SUPFAM; SSF54427; NTF2-like; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000198282}.
FT   DOMAIN          40..147
FT                   /note="NTF2-like N-terminal transpeptidase"
FT                   /evidence="ECO:0000259|Pfam:PF05223"
FT   DOMAIN          243..506
FT                   /note="Penicillin-binding protein transpeptidase"
FT                   /evidence="ECO:0000259|Pfam:PF00905"
SQ   SEQUENCE   509 AA;  52962 MW;  FF68303AA92DC132 CRC64;
     MRSRAVLVLI IVVLLVSGAG VYVLVRPTGP EPGSPAAAGP EETAEAYLSA WQDSDISTMS
     RLVADAPSDF VERHLAFSRD LDIESLTLTP GTLKRQGERA ELPFQGVRGI KDLGNWAFAS
     TLRLALRDGR WKVLWTPETL HPALKDGGRL RFREVPAPGV ELVTRSGVRF PRDSGAEDYL
     GGLNADVGAT ESGYVLEAVA ADGRTEELVT FPPPNAKQIK TTFSRPIQAA AARALDGVDR
     PAAIVAIQAD TGQVLAVADR LGGEGAFRGY YPPGSTFKVI TAAALLSAGL SADSPVRCPA
     TYTPPNGQSI RNAGGDAAPG TITLAGAFAV SCNTTFVEQS ILRLSAGGLV KAAELFGFNQ
     DIKGPGVCGR IEPHGDVDDL RSDAIGQNSV VASPLCMALA AAAVQNGSWH QPSMMKRAAE
     PEDTVALPPG VAAGLRTMMR EVVSSGTASS ANLPAGTAGK TGTAEVNGQE THAWFIGYRG
     KLAFAVFVKN GGSGAQAAVP IAARFLRAL
//