ID A0A239CY49_9ACTN Unreviewed; 368 AA.
AC A0A239CY49;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Transcriptional regulator, LacI family {ECO:0000313|EMBL:SNS24581.1};
GN ORFNames=SAMN06265355_113160 {ECO:0000313|EMBL:SNS24581.1};
OS Actinomadura mexicana.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Thermomonosporaceae; Actinomadura.
OX NCBI_TaxID=134959 {ECO:0000313|EMBL:SNS24581.1, ECO:0000313|Proteomes:UP000198420};
RN [1] {ECO:0000313|EMBL:SNS24581.1, ECO:0000313|Proteomes:UP000198420}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44485 {ECO:0000313|EMBL:SNS24581.1,
RC ECO:0000313|Proteomes:UP000198420};
RA Kim H.J., Triplett B.A.;
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FZNP01000013; SNS24581.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A239CY49; -.
DR Proteomes; UP000198420; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06267; PBP1_LacI_sugar_binding-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF152; HTH-TYPE TRANSCRIPTIONAL REGULATOR EBGR-RELATED; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 41..95
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
FT REGION 1..47
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 368 AA; 39420 MW; 1CB4EF2790B39E5E CRC64;
MSADEANPPH DMLGEGAVPR PRSEPSPVPR DGGQTVPAPK PTIRNVAERA GVSKSLVSLV
MRGSPHVSER RRQAVLQAAR ELGYRPNAVA RSLVEGRTRL IGAIVADLHN PFFAEFLDGL
QESLHGAGLR MLVGSGRWDP MFEAEAVEAF LEMRVDGLVL LSVVPESLKE AAASVPVVVV
GERDVVGVDI VVDDDELGAS LAVDHLVQHG HRRIAHIEGA RSTTARYRRA GYEKAMRRHD
LAGEIVVEPG DFTEDGGYRA ALSLLRRDAR PTAIFAPNDL VATGALSAAD ELGMGVPADL
SIIGYDNTHL AAIRHISLTS VDQPRRDMGR VAAEMLTARI GDPSRVARQK LVVPHLVVRS
TTGPAPAV
//
