ID   A0A239DFD4_9SPHN        Unreviewed;       638 AA.
AC   A0A239DFD4;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=Peptidoglycan glycosyltransferase {ECO:0000313|EMBL:SNS31196.1};
GN   ORFNames=SAMN06295955_101247 {ECO:0000313|EMBL:SNS31196.1};
OS   Sphingopyxis indica.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Sphingopyxis.
OX   NCBI_TaxID=436663 {ECO:0000313|EMBL:SNS31196.1, ECO:0000313|Proteomes:UP000198339};
RN   [1] {ECO:0000313|EMBL:SNS31196.1, ECO:0000313|Proteomes:UP000198339}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DS15 {ECO:0000313|EMBL:SNS31196.1,
RC   ECO:0000313|Proteomes:UP000198339};
RA   Kim H.J., Triplett B.A.;
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
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DR   EMBL; FZPA01000001; SNS31196.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A239DFD4; -.
DR   OrthoDB; 9766847at2; -.
DR   Proteomes; UP000198339; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR   GO; GO:0009002; F:serine-type D-Ala-D-Ala carboxypeptidase activity; IEA:InterPro.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR   Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR   InterPro; IPR012338; Beta-lactam/transpept-like.
DR   InterPro; IPR005311; PBP_dimer.
DR   InterPro; IPR036138; PBP_dimer_sf.
DR   InterPro; IPR001460; PCN-bd_Tpept.
DR   InterPro; IPR017790; Penicillin-binding_protein_2.
DR   NCBIfam; TIGR03423; pbp2_mrdA; 1.
DR   PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR   PANTHER; PTHR30627:SF2; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE MRDA; 1.
DR   Pfam; PF03717; PBP_dimer; 1.
DR   Pfam; PF00905; Transpeptidase; 1.
DR   SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR   SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198339};
KW   Transferase {ECO:0000313|EMBL:SNS31196.1}.
FT   DOMAIN          65..237
FT                   /note="Penicillin-binding protein dimerisation"
FT                   /evidence="ECO:0000259|Pfam:PF03717"
FT   DOMAIN          269..590
FT                   /note="Penicillin-binding protein transpeptidase"
FT                   /evidence="ECO:0000259|Pfam:PF00905"
SQ   SEQUENCE   638 AA;  69211 MW;  F2018D097BA72AA4 CRC64;
     MPRQKRPPIT EAWRGITFTR RALVVGGAQA AVGVALAARM AYISIIDNDR YVLESESNRV
     NLTLVPPRRG WIVDRNGKAM ANNRVSLRID IIPDRLHDKD FVLGQLETLL NLDGDTMQRI
     RRDLKSSSGF QPVAVKEDVS EAEYASVLVR LPDLPGIAPA RGFARYYPTG AAVGHLIGYV
     GAPNAEEYEE AKDPLYITPG FKIGKQALEK YFEPVLRGKP GARRVEVTAR GKVVRELSTQ
     PDVQGQTVQL TVDADLQEYA ARRLGPESGS VVVIDCLTGD VLAMASMPSF DPNSFSSGIG
     VAEYKWLSQN DHVPLRNKTL SGLYPAGSTV KPMVAMSFLE AGLPAEATTF CGGGLRVGNR
     VFHCWNRRGH GQVNMAKGIY QSCDVYFYHF AQQMGMDVIA AMGKRLGLGQ KFPLPVPSQS
     YGTMPSPDWK MEKYGRPWTI ADTVNATIGQ GYVLVNPTQL AVMASRLATG NALMPHLTRD
     ANRAPIQSLG FAPDHIGLVR EAMNQVVNGA GTAGRARLPI EDVKMAGKTG TAQVVSLSKG
     RGGMGVPWKY RDHGLFIAFA PFDAPRYAAA VVIEHGAGSS SAYPVARDVM TFLFDRDKAM
     AALTEYEAGW GGTIEERMAR NFAAWKAGAA QPDPEPGA
//