ID A0A239DGN5_9SPHN Unreviewed; 444 AA.
AC A0A239DGN5;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=MFS transporter, MHS family, proline/betaine transporter {ECO:0000313|EMBL:SNS31447.1};
GN ORFNames=SAMN06295912_10493 {ECO:0000313|EMBL:SNS31447.1};
OS Sphingomonas laterariae.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingomonas.
OX NCBI_TaxID=861865 {ECO:0000313|EMBL:SNS31447.1, ECO:0000313|Proteomes:UP000198281};
RN [1] {ECO:0000313|Proteomes:UP000198281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LNB2 {ECO:0000313|Proteomes:UP000198281};
RA Varghese N., Submissions S.;
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. Metabolite:H+
CC Symporter (MHS) family (TC 2.A.1.6) family.
CC {ECO:0000256|ARBA:ARBA00008240}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FZOS01000004; SNS31447.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A239DGN5; -.
DR OrthoDB; 9783227at2; -.
DR Proteomes; UP000198281; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR005829; Sugar_transporter_CS.
DR PANTHER; PTHR43528; ALPHA-KETOGLUTARATE PERMEASE; 1.
DR PANTHER; PTHR43528:SF1; ALPHA-KETOGLUTARATE PERMEASE; 1.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
DR PROSITE; PS00216; SUGAR_TRANSPORT_1; 1.
DR PROSITE; PS00217; SUGAR_TRANSPORT_2; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000198281};
KW Symport {ECO:0000256|ARBA:ARBA00022847};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022847}.
FT TRANSMEM 61..83
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 95..113
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 119..139
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 160..183
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 195..214
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 248..265
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 285..305
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 317..334
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 340..365
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 372..393
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 405..425
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 24..429
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
SQ SEQUENCE 444 AA; 47653 MW; CB6BC5ADA72428D0 CRC64;
MTALARSPAA TPRPATDHAT LRRAITASAL GNATEWFDYG IYAYGVTYIS AALFPGDVDD
AVLFALATFA ISFLVRPLGG LFWGPMGDRL GRKSVLALTI LLMSGATLCV GLIPDYASIG
MWAPILLILL RMVQGFSTGG EYGGAATFMA EYAPDDRRGF YGSFLEFGTL AGFSLGALLM
LGFSLLLGDA AMHQWGWRIP FLVAAPMGLI GMYLRARMED TPVFLDQHKT GTASPSLALL
VQRHWRPLLV VGGLVVALNV VNYTLLSYMP TYLQRRIGLS ADEALIVPII GMLFMMALLP
FAGALSDRIG RRPMWRWSLI GLIVAVVPLY MLMATGLPGA IAAFILLGLL YVPQLATISA
TFPALFPTSV RFAGFAIAYN VSTSIFGGTA PAIGSGLITI TGNELMPAFY MMLACMIGLA
ALRFMPETAG RSLRDDPFAT ETRP
//
