ID   A0A239EF10_9SPHN        Unreviewed;       481 AA.
AC   A0A239EF10;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   RecName: Full=Phospholipase D {ECO:0000256|ARBA:ARBA00018392};
DE   AltName: Full=Choline phosphatase {ECO:0000256|ARBA:ARBA00029594};
GN   ORFNames=SAMN06295955_101737 {ECO:0000313|EMBL:SNS43119.1};
OS   Sphingopyxis indica.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Sphingopyxis.
OX   NCBI_TaxID=436663 {ECO:0000313|EMBL:SNS43119.1, ECO:0000313|Proteomes:UP000198339};
RN   [1] {ECO:0000313|EMBL:SNS43119.1, ECO:0000313|Proteomes:UP000198339}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DS15 {ECO:0000313|EMBL:SNS43119.1,
RC   ECO:0000313|Proteomes:UP000198339};
RA   Kim H.J., Triplett B.A.;
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Could be a virulence factor. {ECO:0000256|ARBA:ARBA00003145}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Secreted
CC       {ECO:0000256|ARBA:ARBA00004613}.
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DR   EMBL; FZPA01000001; SNS43119.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A239EF10; -.
DR   OrthoDB; 9762009at2; -.
DR   Proteomes; UP000198339; Unassembled WGS sequence.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008808; F:cardiolipin synthase activity; IEA:InterPro.
DR   GO; GO:0032049; P:cardiolipin biosynthetic process; IEA:InterPro.
DR   CDD; cd09152; PLDc_EcCLS_like_1; 1.
DR   CDD; cd09158; PLDc_EcCLS_like_2; 1.
DR   Gene3D; 3.30.870.10; Endonuclease Chain A; 2.
DR   InterPro; IPR022924; Cardiolipin_synthase.
DR   InterPro; IPR027379; CLS_N.
DR   InterPro; IPR025202; PLD-like_dom.
DR   InterPro; IPR001736; PLipase_D/transphosphatidylase.
DR   NCBIfam; TIGR04265; bac_cardiolipin; 1.
DR   PANTHER; PTHR21248; CARDIOLIPIN SYNTHASE; 1.
DR   PANTHER; PTHR21248:SF22; PHOSPHOLIPASE D; 1.
DR   Pfam; PF13091; PLDc_2; 2.
DR   Pfam; PF13396; PLDc_N; 1.
DR   SMART; SM00155; PLDc; 2.
DR   SUPFAM; SSF56024; Phospholipase D/nuclease; 2.
DR   PROSITE; PS50035; PLD; 2.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW   Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Phospholipid biosynthesis {ECO:0000256|ARBA:ARBA00023209};
KW   Phospholipid metabolism {ECO:0000256|ARBA:ARBA00023264};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198339};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        38..56
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          215..242
FT                   /note="PLD phosphodiesterase"
FT                   /evidence="ECO:0000259|PROSITE:PS50035"
FT   DOMAIN          394..421
FT                   /note="PLD phosphodiesterase"
FT                   /evidence="ECO:0000259|PROSITE:PS50035"
SQ   SEQUENCE   481 AA;  52959 MW;  E993DCC3D53FCA48 CRC64;
     MNTDVALALS ILSFAIYAVV IGRILLRPQR EPASRIAWLI ATIAVPVLGV VAYLLLGEAR
     ISAKRRARYR TIEEHLPHPG ENEPVRAGLR ATPYAAPFAL AETVNRLPPT AGNRALLAPD
     SNAAIRMMVE DIDAARESVH LCFYIWLADN NGFRIKDALV RAAKRGVAVR VLADALGSRG
     FIRSAHWIEM RNAGIDARIA LPIGGLVWTL IRGRFDLRNH RKQLIVDNRI AWCGSQNLAD
     PEFRIKSRYA PWVDIMMRWE GPVVQACQFV FAADWESERG DDVGALLQPE AAPPPAAAPG
     IAAQVIATGP NLPYPAMPAC FSALIHAARR ELIVTTPYFV PDEQLLFALL DAARRGVATT
     MIVPRRNDSR IVAAASRSYY DDLIAAGVRL YEYRPGLLHA KTITVDGEVA LVGSANLDRR
     SFELNFENNI LFADPAFTEE VRARQEAYRA DSDAVTAATL ARVGATRRIW RNLLATLSPL
     L
//