ID   A0A239EXE1_9ACTN        Unreviewed;      1062 AA.
AC   A0A239EXE1;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   SubName: Full=Acyl-homoserine lactone (AHL) acylase PvdQ {ECO:0000313|EMBL:SNS49430.1};
GN   ORFNames=SAMN05216276_1010121 {ECO:0000313|EMBL:SNS49430.1};
OS   Streptosporangium subroseum.
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Streptosporangiaceae; Streptosporangium.
OX   NCBI_TaxID=106412 {ECO:0000313|EMBL:SNS49430.1, ECO:0000313|Proteomes:UP000198282};
RN   [1] {ECO:0000313|EMBL:SNS49430.1, ECO:0000313|Proteomes:UP000198282}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 4.2132 {ECO:0000313|EMBL:SNS49430.1,
RC   ECO:0000313|Proteomes:UP000198282};
RA   Kim H.J., Triplett B.A.;
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase S45 family.
CC       {ECO:0000256|ARBA:ARBA00006586}.
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DR   EMBL; FZOD01000010; SNS49430.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A239EXE1; -.
DR   OrthoDB; 5240333at2; -.
DR   Proteomes; UP000198282; Unassembled WGS sequence.
DR   GO; GO:0016811; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; IEA:InterPro.
DR   GO; GO:0017000; P:antibiotic biosynthetic process; IEA:InterPro.
DR   Gene3D; 1.10.1400.10; -; 1.
DR   Gene3D; 2.30.120.10; -; 1.
DR   Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR   Gene3D; 3.60.20.10; Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1; 1.
DR   Gene3D; 1.10.439.10; Penicillin Amidohydrolase, domain 1; 1.
DR   InterPro; IPR000421; FA58C.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR029055; Ntn_hydrolases_N.
DR   InterPro; IPR043147; Penicillin_amidase_A-knob.
DR   InterPro; IPR023343; Penicillin_amidase_dom1.
DR   InterPro; IPR043146; Penicillin_amidase_N_B-knob.
DR   InterPro; IPR002692; S45.
DR   PANTHER; PTHR34218:SF4; ACYL-HOMOSERINE LACTONE ACYLASE QUIP; 1.
DR   PANTHER; PTHR34218; PEPTIDASE S45 PENICILLIN AMIDASE; 1.
DR   Pfam; PF00754; F5_F8_type_C; 1.
DR   Pfam; PF01804; Penicil_amidase; 1.
DR   SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR   SUPFAM; SSF56235; N-terminal nucleophile aminohydrolases (Ntn hydrolases); 1.
DR   PROSITE; PS50022; FA58C_3; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198282};
KW   Signal {ECO:0000256|SAM:SignalP}; Zymogen {ECO:0000256|ARBA:ARBA00023145}.
FT   SIGNAL          1..29
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           30..1062
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5012828205"
FT   DOMAIN          931..1062
FT                   /note="F5/8 type C"
FT                   /evidence="ECO:0000259|PROSITE:PS50022"
FT   REGION          318..362
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1062 AA;  111346 MW;  32382C1661F97C55 CRC64;
     MPARLRRKIT AASAVAILTL ASLVVPASAA VFTPADYCLG ECADILPPGE NGNATLVEIL
     GNQGFGTMPR HSDDQLGKYA NLISGYTGLT DDQITTFFND GSFGVPAGQV ESTTSPRPDV
     KIVRDKATGV PHITGTTRQG TMFGAGYAGA QDRLWVMDLM RHVGRGELTP FAGGAPGNRA
     LEQSAWRNSP YTEADLQGQI NRLRDGSPRG AQLYADVQDY VSGINAYIDR CMANRDCPGE
     YVLTGHMDAI TNAGGPQDFT MTDLIAISGV IGGLFGGGGG AEMQSALVRV AARAKYGTAA
     GDQVWSAFRA QNDPEATLTL HNGQSFPSGN APGATGAVLP DPGTAPVDIT ENETGSATAS
     ATASAPAAKG VLEGMLVDNS KPGMSNAVVV SAAKSASGHP VAVFGPQTGY FAPQLLMLQE
     ISGPGIQARG AAFSGLNFYV LLGRGADYAW SATSSGQDIT DTYALQLCDP GGGTVTKESK
     YYLYHGVCMA METLKKTNAW KPSTADATAA GSYDLVVERT KYGLVSWRGT VGGQPTAFAT
     LRSTYQHEAD SAIGFQMFNE TAQMGDAAAF TNSASNIGFA FNWFYVNSSD AAYFMSGNDP
     VRSAVSDPNL PMPADAAHEW AGFDPSTNTA TYKAPATHPQ TADQDYLVSW NNKQAKDYGA
     ADGNFSFGPV QRADLLDAPV KAALSGSGKL DRAGTVKIMA EAATTDLRGK KVLPDLLRVI
     NSATVTDPAL ASAVSKLSAW AASGARRLET SQGSKAYTNA DAIRAFDAWW PKLVNAQFKP
     GLGAGLYQSL VNALQINESP SGHQQGDLSS LPTSANEAQT HKGSSFQYGW WGYVSKDVRS
     VLGDPVTGPL PSKYCGDGTV AGCRTVLLNS LSAALAEPAA TTYPADDACS AGDQWCADSV
     RQSPLGGIKQ SLISWQNRPT YQQVVSFPAH RGDPIANLAS GGTVKASESQ LFYPASAAVD
     GDPTTRWGSG WNDNQYLQVD LGSAKTVARA VLRWESAYGS AYSIQTSANG STWTTVCSTT
     TGNGGVDNVT FSPVSARYVR MQGAARATSY GYSLYELEAY SR
//