ID A0A239F4F7_9ACTN Unreviewed; 799 AA.
AC A0A239F4F7;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN ORFNames=SAMN05443665_1005159 {ECO:0000313|EMBL:SNS51779.1};
OS Actinomadura meyerae.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Thermomonosporaceae; Actinomadura.
OX NCBI_TaxID=240840 {ECO:0000313|EMBL:SNS51779.1, ECO:0000313|Proteomes:UP000198318};
RN [1] {ECO:0000313|EMBL:SNS51779.1, ECO:0000313|Proteomes:UP000198318}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44715 {ECO:0000313|EMBL:SNS51779.1,
RC ECO:0000313|Proteomes:UP000198318};
RA Kim H.J., Triplett B.A.;
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC {ECO:0000256|ARBA:ARBA00006285}.
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DR EMBL; FZOR01000005; SNS51779.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A239F4F7; -.
DR OrthoDB; 9763537at2; -.
DR Proteomes; UP000198318; Unassembled WGS sequence.
DR GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd06568; GH20_SpHex_like; 1.
DR Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR025705; Beta_hexosaminidase_sua/sub.
DR InterPro; IPR000421; FA58C.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR015883; Glyco_hydro_20_cat.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR029018; Hex-like_dom2.
DR InterPro; IPR015882; HEX_bac_N.
DR PANTHER; PTHR22600; BETA-HEXOSAMINIDASE; 1.
DR PANTHER; PTHR22600:SF21; BETA-HEXOSAMINIDASE A; 1.
DR Pfam; PF00754; F5_F8_type_C; 1.
DR Pfam; PF00728; Glyco_hydro_20; 1.
DR Pfam; PF02838; Glyco_hydro_20b; 1.
DR PRINTS; PR00738; GLHYDRLASE20.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF55545; beta-N-acetylhexosaminidase-like domain; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR PROSITE; PS50022; FA58C_3; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000198318};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..31
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 32..799
FT /note="beta-N-acetylhexosaminidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5013235239"
FT DOMAIN 36..173
FT /note="F5/8 type C"
FT /evidence="ECO:0000259|PROSITE:PS50022"
FT ACT_SITE 508
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR625705-1"
SQ SEQUENCE 799 AA; 84640 MW; 23C9CD164EA6397B CRC64;
MPRPPRPRKR ATAAAMAAAL AFTLTYPLAA AAPASAEAPA ADPVNLALAG TATASSVELD
RDSFAASLVN DGDTGTRWSS KYEDDNWVQV ELPAAANIDH VTLVWPNACA RDFALQTSAD
GASWTTVTRS QHDTCPRTDT IEVGATAKFV RMQGYRRWAS YGYSISEFQI WDRPAPRSLG
LVPKPVSVAE AGGPGYRLGA SASIAAIGSG AKAPADYLAK VLRPSTGYAL PVVTARRGTG
QIVVRVGSGL GPAGRPEGYA LKTNPAGATI EASTANGALN GVQTLRQLFP QWVESPARVR
ADWTVPQVEI TDYPRFAHRG MMLDVARSFY PVDEVKKYID TAAQFKINRL HLHLSDDQGW
RIALDEPADN PSGIEYSKLT SVSGRTAMTY NDAGQLMGTE LGLTGFYTKA DYREIVRYAG
ASGMTVVPEI DMPGHTNAAL HAIPQLNSAG SKPALEPGET TVPANGTPNV GYSSFDAANP
VTYEFTKQVL TQIAELTPGP YLHIGGDESH STSHADYTTM VDAFTGQVNA LGKTVVGWNE
TAGTSLPQNN AVVQFWNGDR NAVAGAVNSR GAKVILSPAG NTYVPQKQDS RQPQGGTWAC
GGPCGLDRHY GWDPGTYIPG ISEQSVLGVE SALWGEWIRR LPQAQYWSYP RLIATAEVGW
TPQAKRDYTD FTGRLAAVGG RLTLQGVNFF PTADVPWPVA ALGADRTVPA GTPSGATWTA
TAPAAGTLTG TVRWSDGVEE NVTLTTSRSA SIPDMRGNAA FTAVSNRTFT ASGTYTATLT
IRPSSGQAPV EAPLTLTVS
//
