ID A0A239FU26_9FIRM Unreviewed; 513 AA.
AC A0A239FU26;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE RecName: Full=Citrate lyase alpha chain {ECO:0000256|PIRNR:PIRNR009451};
DE Short=Citrase alpha chain {ECO:0000256|PIRNR:PIRNR009451};
DE EC=2.8.3.10 {ECO:0000256|PIRNR:PIRNR009451};
DE EC=4.1.3.6 {ECO:0000256|PIRNR:PIRNR009451};
DE AltName: Full=Citrate (pro-3S)-lyase alpha chain {ECO:0000256|PIRNR:PIRNR009451};
DE AltName: Full=Citrate CoA-transferase subunit {ECO:0000256|PIRNR:PIRNR009451};
GN ORFNames=SAMN05446037_10148 {ECO:0000313|EMBL:SNS59414.1};
OS Anaerovirgula multivorans.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Anaerovirgula.
OX NCBI_TaxID=312168 {ECO:0000313|EMBL:SNS59414.1, ECO:0000313|Proteomes:UP000198304};
RN [1] {ECO:0000313|EMBL:SNS59414.1, ECO:0000313|Proteomes:UP000198304}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SCA {ECO:0000313|EMBL:SNS59414.1,
RC ECO:0000313|Proteomes:UP000198304};
RA Kim H.J., Triplett B.A.;
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=acetyl-CoA + citrate = (3S)-citryl-CoA + acetate;
CC Xref=Rhea:RHEA:19405, ChEBI:CHEBI:16947, ChEBI:CHEBI:30089,
CC ChEBI:CHEBI:57288, ChEBI:CHEBI:57321; EC=2.8.3.10;
CC Evidence={ECO:0000256|PIRNR:PIRNR009451};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=citrate = acetate + oxaloacetate; Xref=Rhea:RHEA:10760,
CC ChEBI:CHEBI:16452, ChEBI:CHEBI:16947, ChEBI:CHEBI:30089; EC=4.1.3.6;
CC Evidence={ECO:0000256|PIRNR:PIRNR009451};
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|PIRNR:PIRNR009451}.
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DR EMBL; FZOJ01000014; SNS59414.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A239FU26; -.
DR OrthoDB; 9767643at2; -.
DR Proteomes; UP000198304; Unassembled WGS sequence.
DR GO; GO:0009346; C:ATP-independent citrate lyase complex; IEA:UniProtKB-UniRule.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0008815; F:citrate (pro-3S)-lyase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0008814; F:citrate CoA-transferase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006084; P:acetyl-CoA metabolic process; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.1080.10; Glutaconate Coenzyme A-transferase; 2.
DR InterPro; IPR006472; Citrate_lyase_asu.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR NCBIfam; TIGR01584; citF; 1.
DR PANTHER; PTHR40596; CITRATE LYASE ALPHA CHAIN; 1.
DR PANTHER; PTHR40596:SF1; CITRATE LYASE ALPHA CHAIN; 1.
DR Pfam; PF04223; CitF; 1.
DR PIRSF; PIRSF009451; Citrt_lyas_alpha; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 2.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|PIRNR:PIRNR009451};
KW Lyase {ECO:0000256|PIRNR:PIRNR009451, ECO:0000313|EMBL:SNS59414.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000198304};
KW Transferase {ECO:0000256|PIRNR:PIRNR009451, ECO:0000313|EMBL:SNS59414.1}.
SQ SEQUENCE 513 AA; 55016 MW; B3F5150A4164BF41 CRC64;
MAINKIGREI PDYIEGIGEL KSYEGPFSVE PAKRRFGRKI STITPKQSKI LEDIEQAIIE
TGLKDGMTIS FHHHFREGDY IINMVVDTIA KLGIKNITLA PSSLNSVHAP IIEHIKNGVI
TKIETSGLRG SLADAISKGI LEYPVKIRSH GGRARAIEAG DVKIDVAFLG VPACDEYGNA
NGHSGKSFCG SLGYAKVDAQ YADKVVLITD NLVPYPNVPA SIAQTDVDFV VKMDAIGDPK
GIVSGATRYT KNPRELLIAK YAATVIKESG YLADGFSMQC GTGGASLAVA RSIKQTMIEK
DIKASFALGG ITGQFVEMLE EGLINKLYDT QCFDLTAAKS IGTNPNHVEI DAGFYANPHN
KGCAVNVLDI VILSALEVDT EFNVNVITGS DGVLRGASGG HCDTAAGSKL SIIVAPLIRG
RIPTIVENVN TVITPGETID VVVTDRGIAV NPLRTDLIEK LSKTNLPIFT IEELKEKAEK
IAGKPKAIQY GEKIVALVEY RDGTIIDVIK EVK
//
