ID   A0A239GL55_9ACTN        Unreviewed;       340 AA.
AC   A0A239GL55;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Dimerisation domain-containing protein {ECO:0000313|EMBL:SNS69518.1};
GN   ORFNames=SAMN05216252_107448 {ECO:0000313|EMBL:SNS69518.1};
OS   Actinacidiphila glaucinigra.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Actinacidiphila.
OX   NCBI_TaxID=235986 {ECO:0000313|EMBL:SNS69518.1, ECO:0000313|Proteomes:UP000198280};
RN   [1] {ECO:0000313|EMBL:SNS69518.1, ECO:0000313|Proteomes:UP000198280}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 4.1858 {ECO:0000313|EMBL:SNS69518.1,
RC   ECO:0000313|Proteomes:UP000198280};
RA   Kim H.J., Triplett B.A.;
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FZOF01000007; SNS69518.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A239GL55; -.
DR   OrthoDB; 582216at2; -.
DR   Proteomes; UP000198280; Unassembled WGS sequence.
DR   GO; GO:0008171; F:O-methyltransferase activity; IEA:InterPro.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR031725; ASMT_dimerisation.
DR   InterPro; IPR016461; COMT-like.
DR   InterPro; IPR001077; O_MeTrfase_dom.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR11746:SF327; ACETYLSEROTONIN O-METHYLTRANSFERASE; 1.
DR   PANTHER; PTHR11746; O-METHYLTRANSFERASE; 1.
DR   Pfam; PF16864; Dimerisation2; 1.
DR   Pfam; PF00891; Methyltransf_2; 1.
DR   PIRSF; PIRSF005739; O-mtase; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS51683; SAM_OMT_II; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000198280};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT   DOMAIN          12..93
FT                   /note="Acetylserotonin O-methyltransferase dimerisation"
FT                   /evidence="ECO:0000259|Pfam:PF16864"
FT   DOMAIN          112..322
FT                   /note="O-methyltransferase"
FT                   /evidence="ECO:0000259|Pfam:PF00891"
FT   ACT_SITE        249
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR005739-1"
SQ   SEQUENCE   340 AA;  36886 MW;  D221F0F158A89F37 CRC64;
     MTVDEPITPE PILQLGLGFM ASKTLLSAVE LQVFTVLAAG GRDRDSLAGA VGLHPRSSAD
     FLDALVSLGL LNRDDDGVYH NSPSADVFLD RAKPSYVGGI LEMADTRLFG FWDHLTDALR
     TGVQQNEVTH TGAPFFATLS QDPVAWRNFL NGMNGVSTPL AGALAADFDW TGRRHVADLG
     GALGAVPAAV LRSHPEMTGT VFELPPVRQV FDEYVAAHGL SDRLSFHGGD FFSDPLPAAD
     VYVMGQILHD WNLEQRRFLL RKAYDALPDG GTLIVYDAMI DDDRRRNTYG FMLSLNMLID
     TEGGSEYTVA DATRWLTEAG FAKTSARPLI GGYTAVYATK
//