ID A0A239H059_9BURK Unreviewed; 318 AA.
AC A0A239H059;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=UTP--glucose-1-phosphate uridylyltransferase {ECO:0000256|ARBA:ARBA00019048, ECO:0000256|RuleBase:RU361259};
DE EC=2.7.7.9 {ECO:0000256|ARBA:ARBA00012415, ECO:0000256|RuleBase:RU361259};
DE AltName: Full=UDP-glucose pyrophosphorylase {ECO:0000256|RuleBase:RU361259};
GN ORFNames=SAMN06265795_10615 {ECO:0000313|EMBL:SNS74438.1};
OS Noviherbaspirillum humi.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Oxalobacteraceae; Noviherbaspirillum.
OX NCBI_TaxID=1688639 {ECO:0000313|EMBL:SNS74438.1, ECO:0000313|Proteomes:UP000198284};
RN [1] {ECO:0000313|EMBL:SNS74438.1, ECO:0000313|Proteomes:UP000198284}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=U15 {ECO:0000313|EMBL:SNS74438.1,
RC ECO:0000313|Proteomes:UP000198284};
RA Kim H.J., Triplett B.A.;
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=alpha-D-glucose 1-phosphate + H(+) + UTP = diphosphate + UDP-
CC alpha-D-glucose; Xref=Rhea:RHEA:19889, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:33019, ChEBI:CHEBI:46398, ChEBI:CHEBI:58601,
CC ChEBI:CHEBI:58885; EC=2.7.7.9;
CC Evidence={ECO:0000256|ARBA:ARBA00000872,
CC ECO:0000256|RuleBase:RU361259};
CC -!- SIMILARITY: Belongs to the UDPGP type 2 family.
CC {ECO:0000256|ARBA:ARBA00006890, ECO:0000256|RuleBase:RU361259}.
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DR EMBL; FZOT01000006; SNS74438.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A239H059; -.
DR OrthoDB; 9803306at2; -.
DR Proteomes; UP000198284; Unassembled WGS sequence.
DR GO; GO:0003983; F:UTP:glucose-1-phosphate uridylyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR GO; GO:0006011; P:UDP-glucose metabolic process; IEA:InterPro.
DR CDD; cd02541; UGPase_prokaryotic; 1.
DR InterPro; IPR005771; GalU_uridylyltTrfase_bac/arc.
DR InterPro; IPR005835; NTP_transferase_dom.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR NCBIfam; TIGR01099; galU; 1.
DR PANTHER; PTHR43197; UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE; 1.
DR PANTHER; PTHR43197:SF1; UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE; 1.
DR Pfam; PF00483; NTP_transferase; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 3: Inferred from homology;
KW Nucleotidyltransferase {ECO:0000256|RuleBase:RU361259};
KW Reference proteome {ECO:0000313|Proteomes:UP000198284};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU361259}.
FT DOMAIN 12..269
FT /note="Nucleotidyl transferase"
FT /evidence="ECO:0000259|Pfam:PF00483"
FT REGION 289..318
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 289..310
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 318 AA; 35176 MW; 96EB5ABBE35F999A CRC64;
MQRPVTKAVF PVAGLGTRFL PATKASPKEM LPVVDKPLIQ YAVEEAISAG ITEMIFVTGR
NKRAIEDHFD KAYELEAELE AKNKQALLEV IHSIKPDNVE CFYVRQAEPL GLGHAVLCAE
RMVNNKPFAI ILADDLLYHE QKPVMRQMVD VFSQYGRSVI GVEQIAPEES RSYGVVAGTP
LDERLLKLHG IVEKPAPEDA PSDLGVVGRY VLTPSIFDHL RTIQPGAGGE LQLTDGIASL
LRDEIITAYQ FEGKRYDCGS KLGYLEATVE FALRHPEVGA QFRDFLRQHH GSQTGQRQSD
SGNEPNTILP LQASAWMG
//
