ID   A0A239HA63_9SPHN        Unreviewed;       465 AA.
AC   A0A239HA63;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   24-JAN-2024, entry version 14.
DE   SubName: Full=Alanine or glycine:cation symporter, AGCS family {ECO:0000313|EMBL:SNS78289.1};
GN   ORFNames=SAMN06295912_11613 {ECO:0000313|EMBL:SNS78289.1};
OS   Sphingomonas laterariae.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Sphingomonas.
OX   NCBI_TaxID=861865 {ECO:0000313|EMBL:SNS78289.1, ECO:0000313|Proteomes:UP000198281};
RN   [1] {ECO:0000313|Proteomes:UP000198281}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LNB2 {ECO:0000313|Proteomes:UP000198281};
RA   Varghese N., Submissions S.;
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane
CC       {ECO:0000256|RuleBase:RU363064}; Multi-pass membrane protein
CC       {ECO:0000256|RuleBase:RU363064}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the alanine or glycine:cation symporter (AGCS)
CC       (TC 2.A.25) family. {ECO:0000256|ARBA:ARBA00009261,
CC       ECO:0000256|RuleBase:RU363064}.
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DR   EMBL; FZOS01000016; SNS78289.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A239HA63; -.
DR   Proteomes; UP000198281; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005283; F:amino acid:sodium symporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR   InterPro; IPR001463; Na/Ala_symport.
DR   NCBIfam; TIGR00835; agcS; 1.
DR   PANTHER; PTHR30330; AGSS FAMILY TRANSPORTER, SODIUM-ALANINE; 1.
DR   PANTHER; PTHR30330:SF3; TRANSCRIPTIONAL REGULATOR, LRP FAMILY-RELATED; 1.
DR   Pfam; PF01235; Na_Ala_symp; 1.
DR   PRINTS; PR00175; NAALASMPORT.
PE   3: Inferred from homology;
KW   Cell inner membrane {ECO:0000256|RuleBase:RU363064};
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363064};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198281};
KW   Symport {ECO:0000256|RuleBase:RU363064};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU363064};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU363064};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363064}.
FT   TRANSMEM        7..24
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        30..55
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        106..123
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        160..181
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        201..220
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        227..246
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        252..277
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        317..337
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        357..380
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        401..419
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        425..441
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
SQ   SEQUENCE   465 AA;  49109 MW;  3087EC37BE4F0743 CRC64;
     MIETLSHWID ALAAFVFWKI PFFGTQIEAI VLWLAVPMLF FTLWLGVPQI TGFRFGLRAL
     RGHYADPAHP GEMSQFAALA TALSGTLGLG NIAGVAIAIA AGGPGAAFWL FIIGLFAMAL
     KCAEVTLGLK YREFDDAGRV RGGPMYVMKN GLKARGWPRI GAAIGTLYAV FALGGAIPLV
     QVNQSYAQVS AVVGADFALE YGIGLALAVS LVVVGGARWL GRVTVLLVPA MSLLYLLAAL
     AIIIHHRAEL PAALLTIISD AFTGKAAAGG AIGAFVIGMR RAVYSCEAGV GSAVIAHAAA
     RTREPASEGL VALLEPFIDT VVVCSLTALM IVVSGVWDDG FKDISMASAA FAGVISWFPN
     VLAVAVVLFA YSTLIAWGYY GGQAWAYLFG PSRTATIGYR LLYCLLLPIG ALLDISRVIN
     LIDSAFFLMA LPNVLMLYVF APEVRREIRG YIARKSGAAA EPATA
//