ID   A0A239I8D1_9SPHN        Unreviewed;       569 AA.
AC   A0A239I8D1;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   SubName: Full=3-oxo-5alpha-steroid 4-dehydrogenase {ECO:0000313|EMBL:SNS89642.1};
GN   ORFNames=SAMN06295912_12240 {ECO:0000313|EMBL:SNS89642.1};
OS   Sphingomonas laterariae.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Sphingomonas.
OX   NCBI_TaxID=861865 {ECO:0000313|EMBL:SNS89642.1, ECO:0000313|Proteomes:UP000198281};
RN   [1] {ECO:0000313|Proteomes:UP000198281}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LNB2 {ECO:0000313|Proteomes:UP000198281};
RA   Varghese N., Submissions S.;
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|ARBA:ARBA00001974};
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DR   EMBL; FZOS01000022; SNS89642.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A239I8D1; -.
DR   OrthoDB; 3178130at2; -.
DR   Proteomes; UP000198281; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR   Gene3D; 3.90.700.10; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR   InterPro; IPR003953; FAD-binding_2.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR   PANTHER; PTHR43400:SF7; FAD_BINDING_2 DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR43400; FUMARATE REDUCTASE; 1.
DR   Pfam; PF00890; FAD_binding_2; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   SUPFAM; SSF56425; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
PE   4: Predicted;
KW   Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198281}.
FT   DOMAIN          33..540
FT                   /note="FAD-dependent oxidoreductase 2 FAD binding"
FT                   /evidence="ECO:0000259|Pfam:PF00890"
SQ   SEQUENCE   569 AA;  60985 MW;  76A43497D9D12A38 CRC64;
     MGVAAKAQEV GLDVEDPLIL DDVAAHMWDE EADLVVAGLG GAGVAAAVEA LERGVSVIAV
     DRYEGGGSTA ANGGIFYAGG GTVIQKEAGE DDTPEEMYKY LKMEAGDVVA DSTLRKFVDE
     SVSTVDWILH HGGKLKGTVW KKKASYPPLD RFLYHPDNSL VARYKKVAKP AARGHRAHIA
     NGKKAWGVGI GIYNPLRDSA LKLGLKFRPL TEARQLAIDA NGRVVGLKVL TIPPGSKDAT
     AFTNHIRRAN FFLAMLPPSL PFAAITIGIG NHYLKKAMRI EAHGRETRWI RAKEGVLLST
     GGFIMNPRMV QHYAPAYAAG MPNGTLGDQG SGIIMGMTAG GSTALMGKVS AWRFINPPKA
     WSDAIVVNAK GERFVDETVY GATMGEHIVD HHGGSGWLIY DANLRKQAFS QAFDPVLVPF
     QRDVTLLNLL FNYKKAPTLD ALADKIGLDR ATIAATVAAY NRAARGEEAD RFEKEPPDMQ
     VIEQGPYYAM DISIASKFLP LPVITFGGLR VEENTGQVLD GGGKPIPGLY AAGRTAVGIA
     SQTYVSGLSY ADCVFSGRRA ARHIAKANV
//