ID   A0A239JVG5_9ACTN        Unreviewed;       669 AA.
AC   A0A239JVG5;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   SubName: Full=ATP-dependent exoDNAse (Exonuclease V), alpha subunit, helicase superfamily I {ECO:0000313|EMBL:SNT09448.1};
GN   ORFNames=SAMN05216252_11432 {ECO:0000313|EMBL:SNT09448.1};
OS   Actinacidiphila glaucinigra.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Actinacidiphila.
OX   NCBI_TaxID=235986 {ECO:0000313|EMBL:SNT09448.1, ECO:0000313|Proteomes:UP000198280};
RN   [1] {ECO:0000313|EMBL:SNT09448.1, ECO:0000313|Proteomes:UP000198280}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 4.1858 {ECO:0000313|EMBL:SNT09448.1,
RC   ECO:0000313|Proteomes:UP000198280};
RA   Kim H.J., Triplett B.A.;
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FZOF01000014; SNT09448.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A239JVG5; -.
DR   OrthoDB; 9763659at2; -.
DR   Proteomes; UP000198280; Unassembled WGS sequence.
DR   GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   CDD; cd18809; SF1_C_RecD; 1.
DR   Gene3D; 2.30.30.940; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR029493; RecD-like_HHH.
DR   InterPro; IPR027785; UvrD-like_helicase_C.
DR   Pfam; PF13604; AAA_30; 1.
DR   Pfam; PF14490; HHH_4; 1.
DR   Pfam; PF13538; UvrD_C_2; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000313|EMBL:SNT09448.1};
KW   Exonuclease {ECO:0000313|EMBL:SNT09448.1};
KW   Helicase {ECO:0000313|EMBL:SNT09448.1};
KW   Hydrolase {ECO:0000313|EMBL:SNT09448.1};
KW   Nuclease {ECO:0000313|EMBL:SNT09448.1};
KW   Nucleotide-binding {ECO:0000313|EMBL:SNT09448.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198280}.
FT   DOMAIN          105..187
FT                   /note="RecD helicase-like helix-hairpin-helix"
FT                   /evidence="ECO:0000259|Pfam:PF14490"
FT   DOMAIN          584..632
FT                   /note="UvrD-like helicase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13538"
FT   REGION          1..91
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..29
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        74..88
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   669 AA;  68284 MW;  AEAD8E12AD7EB6F2 CRC64;
     MTEDREDRDR EDRAEPEETA GEETAAPRRP RPSTEGVGSQ LPAELTDLAA AVRAIERGER
     PAAPVKRGGP ARPAAAPSPA PAPAPVARPS LPAQLSGDAV AAARTVLAAG GAPESLAEAA
     VEALGERAGD ALREDPWQIL ALAGIRVEQA DGFAKTLLGG EGGPGDERRV RALVVWLLER
     AAERGHTALE WGTLGAALGQ NGVADAEETL KAAVADGLVL VFHVPDESAG ARTAADDEDE
     EAPVRLLLGL DRFALAEESL ADGLSRLLNT FDADGSQDWE GAAGAAPSPS AAALVRAAAG
     SGLVAHTGAE AAREEPAALV AAARSLGLRA WAVAATEDGR RRLAGAVDAD ATATLAGLLS
     GHEGPGRDED GALALDLLAV LDAPQLDVET AATLVESVPD GARLVLSGDP AVLWSPGPGR
     VFADLLAAKV CPQVASRTPD PGPVGELVSG IGFGELAEVD APGKEVVIVP VRDAGEAVHR
     TVQLVADSVP RVIGVPPEHT QVITPGHGGA AGTRALNAAL KERLNRGPGR FGGFDPGDRI
     MYAPAAGTAV PGTVVSADAQ GLRLDCGGTP VVVAPDAVAA EVRHGWAVTA HQAAGRRWPA
     AVVVLPGDSA QALTRAWVYT AFSRGERHLS VVQGIEQALP RVVAEVPARD RTTRLRDILR
     EQAAAAAAE
//