ID   A0A239K7L1_9ACTN        Unreviewed;       351 AA.
AC   A0A239K7L1;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Adenosine deaminase {ECO:0000313|EMBL:SNT13991.1};
GN   ORFNames=SAMN06264365_1442 {ECO:0000313|EMBL:SNT13991.1};
OS   Actinoplanes regularis.
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Actinoplanes.
OX   NCBI_TaxID=52697 {ECO:0000313|EMBL:SNT13991.1, ECO:0000313|Proteomes:UP000198415};
RN   [1] {ECO:0000313|EMBL:SNT13991.1, ECO:0000313|Proteomes:UP000198415}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 43151 {ECO:0000313|EMBL:SNT13991.1,
RC   ECO:0000313|Proteomes:UP000198415};
RA   Kim H.J., Triplett B.A.;
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SIMILARITY: Belongs to the metallo-dependent hydrolases superfamily.
CC       Adenosine and AMP deaminases family. {ECO:0000256|ARBA:ARBA00006676}.
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DR   EMBL; FZNR01000044; SNT13991.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A239K7L1; -.
DR   OrthoDB; 105475at2; -.
DR   Proteomes; UP000198415; Unassembled WGS sequence.
DR   GO; GO:0019239; F:deaminase activity; IEA:InterPro.
DR   Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR   InterPro; IPR001365; A_deaminase_dom.
DR   InterPro; IPR006330; Ado/ade_deaminase.
DR   InterPro; IPR032466; Metal_Hydrolase.
DR   NCBIfam; TIGR01430; aden_deam; 1.
DR   PANTHER; PTHR43114; ADENINE DEAMINASE; 1.
DR   PANTHER; PTHR43114:SF6; ADENINE DEAMINASE; 1.
DR   Pfam; PF00962; A_deaminase; 1.
DR   SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000198415}.
FT   DOMAIN          13..336
FT                   /note="Adenosine deaminase"
FT                   /evidence="ECO:0000259|Pfam:PF00962"
SQ   SEQUENCE   351 AA;  37442 MW;  364307C2675525AA CRC64;
     MALDLTDFIA GLPKVELHVH HVGSAAPQTV ARLAERYAGD TSVPADPALL AEYFTFTDFA
     HFIKVYLSVV DLIRDAEDVA TLTYDIGAGL AAQSVRYAEV TLSPYSHITR GIPAEAYCEA
     VEDARRRAAR DHGVELRWCF DIPGPPPWMT AADVTLDVAL KQRPDGLISF GLGGPEAGVS
     REQFAGHFAA ARAAGLHSVP HAGESTGPQT VWDAVRHLGA ERIGHGIAAA RDPELMAHLR
     EHDIALEVCP TSNVCTRSVP SLAEHPLPAL VAAGVPVTIN SDDPPMFSTT LNREYQVAAD
     LLGLDERGVA GLARQAVRYS FLDDAGKSAI LAEIDAYVAG SGWVQALTDQ N
//