ID   A0A239KR97_9BURK        Unreviewed;       437 AA.
AC   A0A239KR97;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=O-acetylhomoserine sulfhydrylase {ECO:0000313|EMBL:SNT20550.1};
GN   ORFNames=SAMN06265795_11719 {ECO:0000313|EMBL:SNT20550.1};
OS   Noviherbaspirillum humi.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Oxalobacteraceae; Noviherbaspirillum.
OX   NCBI_TaxID=1688639 {ECO:0000313|EMBL:SNT20550.1, ECO:0000313|Proteomes:UP000198284};
RN   [1] {ECO:0000313|EMBL:SNT20550.1, ECO:0000313|Proteomes:UP000198284}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=U15 {ECO:0000313|EMBL:SNT20550.1,
RC   ECO:0000313|Proteomes:UP000198284};
RA   Kim H.J., Triplett B.A.;
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933,
CC         ECO:0000256|RuleBase:RU362118};
CC   -!- SIMILARITY: Belongs to the trans-sulfuration enzymes family.
CC       {ECO:0000256|ARBA:ARBA00009077, ECO:0000256|RuleBase:RU362118}.
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DR   EMBL; FZOT01000017; SNT20550.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A239KR97; -.
DR   OrthoDB; 9805807at2; -.
DR   Proteomes; UP000198284; Unassembled WGS sequence.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0016765; F:transferase activity, transferring alkyl or aryl (other than methyl) groups; IEA:InterPro.
DR   GO; GO:0019346; P:transsulfuration; IEA:InterPro.
DR   CDD; cd00614; CGS_like; 1.
DR   Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR000277; Cys/Met-Metab_PyrdxlP-dep_enz.
DR   InterPro; IPR006235; OAc-hSer/O-AcSer_sulfhydrylase.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   NCBIfam; TIGR01326; OAH_OAS_sulfhy; 1.
DR   PANTHER; PTHR43797; HOMOCYSTEINE/CYSTEINE SYNTHASE; 1.
DR   PANTHER; PTHR43797:SF2; HOMOCYSTEINE_CYSTEINE SYNTHASE; 1.
DR   Pfam; PF01053; Cys_Met_Meta_PP; 1.
DR   PIRSF; PIRSF001434; CGS; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR   PROSITE; PS00868; CYS_MET_METAB_PP; 1.
PE   3: Inferred from homology;
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW   ECO:0000256|PIRSR:PIRSR001434-2};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198284}.
FT   MOD_RES         211
FT                   /note="N6-(pyridoxal phosphate)lysine"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001434-2"
SQ   SEQUENCE   437 AA;  46876 MW;  840C1E5BCB6A6E4B CRC64;
     MSGEPHYPGF DTLALHAGAA PDPATGARAT PIYLTTSFVF KDSDHAAALF NMERAGHVYS
     RISNPTNAVL EERIAALEGG VAGLAVASGQ AAMHLGLSTI AGAGSHIVAS RALYGGSQNL
     LAYTLKRFGI ETTFVNPRDI DAWRAAIRPN TKVLFGETLG NPGLDVLDIP RLSQLAHEHH
     LPLMVDGTFT TPYLLKPFDH GADLVFHSAT KFLCGHGTAI GGLLVDGGTF DWQLAYEKTG
     RFAELCEPYD GFHGMVFTEE SSVAAFSLRA RREGLRDFGA VMSPHNAFAI LQGIETLSLR
     MERHVANTRR VVAFLAAHPA VESVSYPELE NHPDHALARQ LLPRGCGAVF SFSIKGDRAA
     GRRFVEALRI FSHLANVGDA KSLVIHPAST THFRVPAAQL EAAGIREGTM RLSVGLEDAD
     DLIEDLSRGL RAAQKGA
//