ID   A0A239LES4_9ACTN        Unreviewed;       356 AA.
AC   A0A239LES4;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=Aminodeoxyfutalosine deaminase {ECO:0000313|EMBL:SNT28981.1};
GN   ORFNames=SAMN05216276_103288 {ECO:0000313|EMBL:SNT28981.1};
OS   Streptosporangium subroseum.
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Streptosporangiaceae; Streptosporangium.
OX   NCBI_TaxID=106412 {ECO:0000313|EMBL:SNT28981.1, ECO:0000313|Proteomes:UP000198282};
RN   [1] {ECO:0000313|EMBL:SNT28981.1, ECO:0000313|Proteomes:UP000198282}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 4.2132 {ECO:0000313|EMBL:SNT28981.1,
RC   ECO:0000313|Proteomes:UP000198282};
RA   Kim H.J., Triplett B.A.;
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SIMILARITY: Belongs to the metallo-dependent hydrolases superfamily.
CC       Adenosine and AMP deaminases family. {ECO:0000256|ARBA:ARBA00006676}.
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DR   EMBL; FZOD01000032; SNT28981.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A239LES4; -.
DR   Proteomes; UP000198282; Unassembled WGS sequence.
DR   GO; GO:0019239; F:deaminase activity; IEA:InterPro.
DR   Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR   InterPro; IPR001365; A_deaminase_dom.
DR   InterPro; IPR006330; Ado/ade_deaminase.
DR   InterPro; IPR032466; Metal_Hydrolase.
DR   NCBIfam; TIGR01430; aden_deam; 1.
DR   PANTHER; PTHR43114; ADENINE DEAMINASE; 1.
DR   PANTHER; PTHR43114:SF6; ADENINE DEAMINASE; 1.
DR   Pfam; PF00962; A_deaminase; 1.
DR   SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000198282}.
FT   DOMAIN          25..347
FT                   /note="Adenosine deaminase"
FT                   /evidence="ECO:0000259|Pfam:PF00962"
SQ   SEQUENCE   356 AA;  39041 MW;  48D9617732DB7C57 CRC64;
     MSFRRGLDAP KVGRMTIDAF IDALPKVELH VHLIGSASVP TVLELSRRHP DSRVPTTEEE
     LRAFYGFRDF PHFAEVYRAV NALVRTPEDV ATLVTGLAGD LARQNGRYVE LTVTPYAHHI
     MGMPMREVTE ALDLAARRSR DEYGLQVAYI FDIPGEYGVE AARVTLDHAL REPPEALVGF
     GLAGIEQERP QHRDAFRDAF RAATAAGLRS LPHAGEMNGP EPIWEALDHL GAERIGHGIA
     CLDDPRLVAH LRETRIPLEV CPTSNVCTGQ VAHIKEHPFP RLLEEGLFVT LNSDDPPMFA
     TTLSSEYRVA AEVFGLDREA LTGLARNAVN ASCLDPAGKQ TLLAEIDGLP TDPATP
//