ID   A0A239P079_9ACTN        Unreviewed;       830 AA.
AC   A0A239P079;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=von Willebrand factor type A domain-containing protein {ECO:0000313|EMBL:SNT60382.1};
GN   ORFNames=SAMN05443665_10575 {ECO:0000313|EMBL:SNT60382.1};
OS   Actinomadura meyerae.
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Thermomonosporaceae; Actinomadura.
OX   NCBI_TaxID=240840 {ECO:0000313|EMBL:SNT60382.1, ECO:0000313|Proteomes:UP000198318};
RN   [1] {ECO:0000313|EMBL:SNT60382.1, ECO:0000313|Proteomes:UP000198318}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44715 {ECO:0000313|EMBL:SNT60382.1,
RC   ECO:0000313|Proteomes:UP000198318};
RA   Kim H.J., Triplett B.A.;
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FZOR01000057; SNT60382.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A239P079; -.
DR   Proteomes; UP000198318; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd00198; vWFA; 1.
DR   Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   NCBIfam; NF041940; choice_anch_X; 1.
DR   Pfam; PF00092; VWA; 1.
DR   SMART; SM00327; VWA; 1.
DR   SUPFAM; SSF53300; vWA-like; 1.
DR   PROSITE; PS50234; VWFA; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198318};
KW   Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..30
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           31..830
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5039726705"
FT   TRANSMEM        625..643
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          66..278
FT                   /note="VWFA"
FT                   /evidence="ECO:0000259|PROSITE:PS50234"
FT   REGION          728..830
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        786..801
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   830 AA;  86016 MW;  46400CE7EC1BCDA8 CRC64;
     MTGRASACPL RITMAAVVTA VQLGPLAAPA AAAPAAARAA GPAARAAGPT ARAAGPTAAP
     EPTLMDVSIL VDESGSLSDA DVREEIKAAT SIALSGLNPR SRVSVYGFGS QNRPGQNAIT
     EACPPTVLDS SVKKDALGAC IRKIHRRADG EGNDTDHAAA LAKGLSALGT GGPEGALKVV
     FLLTDGRLDV HRSPHYGRIE IDRNREAEKQ VETQLALASS GRVQVWPLGF GSGIDHAALE
     RFAAGGYQGA CDGRTASRPK ARVVRDSGDV VRSLTDAFAA AGCAGVSRSD ETTLGPGQTR
     ELKIDIPIIA TDGNITVAKG DPRVRVDYVQ PGGETVVPNG RSGQSEFKRA GENAGVETLH
     IVNPRNGTWT IRLTAPDKLA KQLVSATAIW QGAVSSSLVV EPPSARTGQP LTVRLSLVTR
     QGAVTDRKAL SGLNFTVQAT GPSLGAPQSI IIRDDGKAPD DRADDGRYAG TFTAPGRPGD
     LTFTGVVSGY GIHADKLPVT VAVGAQAPAL QGRVEFSADP VVHPGAEVRG KVTMENAGAP
     VRGRIVLEGA GRAGGAVLAG NTDLAIGTGA TSRPFTVRFP DDAALGGTSM TVKVVDAADL
     SKVYANGQLT VTVKEPPGWL ERNRFLIAGA VLLLLALALL LHLRRRAWKA GVDVRWLRAS
     LRQDGEEVAR LKAPSKWAQE FRFVVHDGSA GEPGLDYPKA GDRPVRARRG APGKVVVQLP
     DGPRYEIAVG GDGEPLEETG LTLAFTDDRP RRVRAGRGGT GRGTGARRGA SGTRDTPGRS
     TADRTASDRT ASDRTGPDRT APDRGGETSG AARTGPAGTA RPAYEDDPWL
//