ID A0A239PAL8_9ACTN Unreviewed; 310 AA.
AC A0A239PAL8;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Adenosine deaminase {ECO:0000313|EMBL:SNT64196.1};
GN ORFNames=SAMN05421812_116146 {ECO:0000313|EMBL:SNT64196.1};
OS Asanoa hainanensis.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Asanoa.
OX NCBI_TaxID=560556 {ECO:0000313|EMBL:SNT64196.1, ECO:0000313|Proteomes:UP000198362};
RN [1] {ECO:0000313|EMBL:SNT64196.1, ECO:0000313|Proteomes:UP000198362}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 4.5593 {ECO:0000313|EMBL:SNT64196.1,
RC ECO:0000313|Proteomes:UP000198362};
RA Kim H.J., Triplett B.A.;
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: Belongs to the metallo-dependent hydrolases superfamily.
CC Adenosine and AMP deaminases family. {ECO:0000256|ARBA:ARBA00006676}.
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DR EMBL; FZPH01000016; SNT64196.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A239PAL8; -.
DR Proteomes; UP000198362; Unassembled WGS sequence.
DR GO; GO:0019239; F:deaminase activity; IEA:InterPro.
DR GO; GO:0016814; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines; IEA:UniProt.
DR GO; GO:0009168; P:purine ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
DR Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR InterPro; IPR006650; A/AMP_deam_AS.
DR InterPro; IPR001365; A_deaminase_dom.
DR InterPro; IPR006330; Ado/ade_deaminase.
DR InterPro; IPR032466; Metal_Hydrolase.
DR NCBIfam; TIGR01430; aden_deam; 1.
DR PANTHER; PTHR43114; ADENINE DEAMINASE; 1.
DR PANTHER; PTHR43114:SF6; ADENINE DEAMINASE; 1.
DR Pfam; PF00962; A_deaminase; 1.
DR SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
DR PROSITE; PS00485; A_DEAMINASE; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000198362}.
FT DOMAIN 7..309
FT /note="Adenosine deaminase"
FT /evidence="ECO:0000259|Pfam:PF00962"
SQ SEQUENCE 310 AA; 31846 MW; 7B3D0DFE31F3E2F3 CRC64;
MTAATLPKTN LHLHLTGAMR PSTLAELAAR DGLPLPPPFA PGTVHEWAAF QERYDLARAT
IRGPADIERL VVEAAEDDAT CGARWLELQV DPTSYAVVAG SLHGAVEAAL TGAARAPIPV
GIVVAASWAA GPEHALRLAK LAAAYADRGV VGFGLSNDER LGRVEDMAPA CRLAAEAGLL
VVPHGGFYTP PAHVADCVTV LGAHRIGHGL AAMHDPATRD LLAEGGVALE VCPTSYPPLG
VAAITELPIR DLRAAGVLVA LGTDDPLLFG SDLTTQYALV TSDPAEQADL ARCSVMASAA
PAALKAALLG
//
