ID A0A239PXD4_9RHOB Unreviewed; 335 AA.
AC A0A239PXD4;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=3-hydroxyisobutyryl-CoA hydrolase {ECO:0000256|ARBA:ARBA00011915};
DE EC=3.1.2.4 {ECO:0000256|ARBA:ARBA00011915};
GN ORFNames=SAMN05444959_10741 {ECO:0000313|EMBL:SNT74327.1};
OS Paracoccus seriniphilus.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae; Paracoccus.
OX NCBI_TaxID=184748 {ECO:0000313|EMBL:SNT74327.1, ECO:0000313|Proteomes:UP000198307};
RN [1] {ECO:0000313|EMBL:SNT74327.1, ECO:0000313|Proteomes:UP000198307}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14827 {ECO:0000313|EMBL:SNT74327.1,
RC ECO:0000313|Proteomes:UP000198307};
RA Sun Z.S., Albrecht U., Echele G., Lee C.C.;
RL Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=3-hydroxy-2-methylpropanoyl-CoA + H2O = 3-hydroxy-2-
CC methylpropanoate + CoA + H(+); Xref=Rhea:RHEA:20888,
CC ChEBI:CHEBI:11805, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57340; EC=3.1.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00001709};
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DR EMBL; FZQB01000007; SNT74327.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A239PXD4; -.
DR OrthoDB; 9790967at2; -.
DR Proteomes; UP000198307; Unassembled WGS sequence.
DR GO; GO:0003860; F:3-hydroxyisobutyryl-CoA hydrolase activity; IEA:InterPro.
DR CDD; cd06558; crotonase-like; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR045004; ECH_dom.
DR InterPro; IPR032259; HIBYL-CoA-H.
DR PANTHER; PTHR43176:SF3; 3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43176; 3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED; 1.
DR Pfam; PF16113; ECH_2; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000198307}.
FT DOMAIN 13..311
FT /note="Enoyl-CoA hydratase/isomerase"
FT /evidence="ECO:0000259|Pfam:PF16113"
FT REGION 203..223
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 335 AA; 36359 MW; 434E16B29E6BA20E CRC64;
MQDLNIRISG KAGRITFTRP KALNALSHDM ALEIQAALDA WCDDPAVSLV VIDAEGDRAF
CAGGDIAAVY RAGISGDHSV GRAFFRDEYL LNATIAEYPK PIVAFMQGFI MGGGVGIGGH
AQQRIVGDSS QIAMPESGIG LIPDVGGTWL LAHAPGRIGE YLALTGGRMG AGDAIHAGFA
DVYLPEARWP ELIRTLEQTG DFNRIKGETP PESPLATRDL SPFGQPDLKS ITAALEEAGD
ESSLKAIRRN SPLSMAAGLR MVREARRDPS IRESLAREFR FTYRATEFAD FLEGVRAQII
DKDRNPNWQA DPSPENLDRM LAPLGEHEMK WETGK
//
