ID A0A239Q4S2_9RHOB Unreviewed; 361 AA.
AC A0A239Q4S2;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 24-JAN-2024, entry version 12.
DE RecName: Full=UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) {ECO:0000256|ARBA:ARBA00038858};
DE EC=5.1.3.14 {ECO:0000256|ARBA:ARBA00038858};
GN ORFNames=SAMN05444959_1442 {ECO:0000313|EMBL:SNT76937.1};
OS Paracoccus seriniphilus.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae; Paracoccus.
OX NCBI_TaxID=184748 {ECO:0000313|EMBL:SNT76937.1, ECO:0000313|Proteomes:UP000198307};
RN [1] {ECO:0000313|EMBL:SNT76937.1, ECO:0000313|Proteomes:UP000198307}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14827 {ECO:0000313|EMBL:SNT76937.1,
RC ECO:0000313|Proteomes:UP000198307};
RA Sun Z.S., Albrecht U., Echele G., Lee C.C.;
RL Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=UDP-N-acetyl-alpha-D-glucosamine = UDP-N-acetyl-alpha-D-
CC mannosamine; Xref=Rhea:RHEA:17213, ChEBI:CHEBI:57705,
CC ChEBI:CHEBI:68623; EC=5.1.3.14;
CC Evidence={ECO:0000256|ARBA:ARBA00036080};
CC -!- SIMILARITY: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
CC {ECO:0000256|ARBA:ARBA00038209, ECO:0000256|RuleBase:RU003513}.
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DR EMBL; FZQB01000044; SNT76937.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A239Q4S2; -.
DR Proteomes; UP000198307; Unassembled WGS sequence.
DR GO; GO:0008761; F:UDP-N-acetylglucosamine 2-epimerase activity; IEA:InterPro.
DR CDD; cd03786; GTB_UDP-GlcNAc_2-Epimerase; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR InterPro; IPR003331; UDP_GlcNAc_Epimerase_2_dom.
DR InterPro; IPR029767; WecB-like.
DR NCBIfam; TIGR00236; wecB; 1.
DR PANTHER; PTHR43174; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR PANTHER; PTHR43174:SF2; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR Pfam; PF02350; Epimerase_2; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000256|RuleBase:RU003513};
KW Reference proteome {ECO:0000313|Proteomes:UP000198307}.
FT DOMAIN 8..354
FT /note="UDP-N-acetylglucosamine 2-epimerase"
FT /evidence="ECO:0000259|Pfam:PF02350"
SQ SEQUENCE 361 AA; 39756 MW; CD325AF3A5062B17 CRC64;
MAPVVTGLAS DERFESQVCI TAQHREMLDQ VTSLFGIRPE YDLDVMKPGQ DLTGVTSDIL
LGLRDVLAEA RPDMVLVHGD TATTLSATLA AYYARIPIGH VEAGLRTGDL YSPWPEEGNR
RVTGALADLH FAPTETSRAS LRRENTPDDQ IIVTGNTVID ALLQVVERIR NDAALSAELA
ERFSFIEPGR RVVLVTGHRR ESFGGGFERI CQALRQIADR FPDVDLVYPM HMNPNVREPV
QRILGGADNI HLIEPLDYLP FVWLMSRSDI IVTDSGGIQE EAPSLGKPVL VMRDTTERPE
AVDAGTVRLV GTDTDLIVQQ VSLLLSDQSA YDQMSFAHNP YGDGKAVARI LDALAQFKDK
K
//
