ID A0A239QS98_9MICO Unreviewed; 322 AA.
AC A0A239QS98;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=23S rRNA (Guanosine2251-2'-O)-methyltransferase {ECO:0000313|EMBL:SNU01428.1};
GN ORFNames=SAMN06298212_11113 {ECO:0000313|EMBL:SNU01428.1};
OS Ruaniaceae bacterium KH17.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Ruaniaceae.
OX NCBI_TaxID=1945888 {ECO:0000313|EMBL:SNU01428.1, ECO:0000313|Proteomes:UP000214750};
RN [1] {ECO:0000313|EMBL:SNU01428.1, ECO:0000313|Proteomes:UP000214750}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KH17 {ECO:0000313|EMBL:SNU01428.1,
RC ECO:0000313|Proteomes:UP000214750};
RA Sun Z.S., Albrecht U., Echele G., Lee C.C.;
RL Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the class IV-like SAM-binding methyltransferase
CC superfamily. RNA methyltransferase TrmH family.
CC {ECO:0000256|ARBA:ARBA00007228}.
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DR EMBL; FZQV01000011; SNU01428.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A239QS98; -.
DR OrthoDB; 9785673at2; -.
DR Proteomes; UP000214750; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR CDD; cd18103; SpoU-like_RlmB; 1.
DR Gene3D; 3.30.1330.30; -; 1.
DR Gene3D; 3.40.1280.10; -; 1.
DR InterPro; IPR029028; Alpha/beta_knot_MTases.
DR InterPro; IPR029064; Ribosomal_eL30-like_sf.
DR InterPro; IPR004441; rRNA_MeTrfase_TrmH.
DR InterPro; IPR001537; SpoU_MeTrfase.
DR InterPro; IPR013123; SpoU_subst-bd.
DR InterPro; IPR029026; tRNA_m1G_MTases_N.
DR NCBIfam; TIGR00186; rRNA_methyl_3; 1.
DR PANTHER; PTHR46429; 23S RRNA (GUANOSINE-2'-O-)-METHYLTRANSFERASE RLMB; 1.
DR PANTHER; PTHR46429:SF1; 23S RRNA (GUANOSINE-2'-O-)-METHYLTRANSFERASE RLMB; 1.
DR Pfam; PF00588; SpoU_methylase; 1.
DR Pfam; PF08032; SpoU_sub_bind; 1.
DR SMART; SM00967; SpoU_sub_bind; 1.
DR SUPFAM; SSF75217; alpha/beta knot; 1.
DR SUPFAM; SSF55315; L30e-like; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000313|EMBL:SNU01428.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000214750};
KW Transferase {ECO:0000313|EMBL:SNU01428.1}.
FT DOMAIN 79..155
FT /note="RNA 2-O ribose methyltransferase substrate binding"
FT /evidence="ECO:0000259|SMART:SM00967"
FT REGION 1..70
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 31..64
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 322 AA; 33662 MW; E3A5D7F5E8464409 CRC64;
MAGNSQRKGA VRKGGSRQKV GSGGQRRRGL EGKGPTPKAE DRTYHAAHKR KQESDRREAA
APKRRTPGWV KALPRDTEFV VGRNAVTEAV GAGIPILGVY AAGGLSGDER VSEVLRAATE
SGAPLYEVTR GELEAISAGQ SHQGIAIAVP PHEYADLDDL VARASEKLTL PLFVALDGVT
DPHNLGAVIR SAGAFGADGV IIPERRAAGV TASVWKVSAG ALAHVEVARV TNLVRALTDL
KTQGYFVVGL DGVGAIDIGT LELYDQPLVL VTGAEGAGLS RLVRETCDVT AAIPISANVE
SLNAAVATGI CLYQVTQLRE KK
//
