ID A0A239QTI2_9MICO Unreviewed; 473 AA.
AC A0A239QTI2;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Xaa-Pro aminopeptidase {ECO:0000313|EMBL:SNU01924.1};
GN ORFNames=SAMN06298212_12027 {ECO:0000313|EMBL:SNU01924.1};
OS Ruaniaceae bacterium KH17.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Ruaniaceae.
OX NCBI_TaxID=1945888 {ECO:0000313|EMBL:SNU01924.1, ECO:0000313|Proteomes:UP000214750};
RN [1] {ECO:0000313|EMBL:SNU01924.1, ECO:0000313|Proteomes:UP000214750}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KH17 {ECO:0000313|EMBL:SNU01924.1,
RC ECO:0000313|Proteomes:UP000214750};
RA Sun Z.S., Albrecht U., Echele G., Lee C.C.;
RL Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC Evidence={ECO:0000256|ARBA:ARBA00001936};
CC -!- SIMILARITY: Belongs to the peptidase M24B family.
CC {ECO:0000256|ARBA:ARBA00008766}.
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DR EMBL; FZQV01000020; SNU01924.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A239QTI2; -.
DR OrthoDB; 9806388at2; -.
DR Proteomes; UP000214750; Unassembled WGS sequence.
DR GO; GO:0030145; F:manganese ion binding; IEA:InterPro.
DR GO; GO:0070006; F:metalloaminopeptidase activity; IEA:InterPro.
DR CDD; cd01087; Prolidase; 1.
DR Gene3D; 3.90.230.10; Creatinase/methionine aminopeptidase superfamily; 1.
DR Gene3D; 3.40.350.10; Creatinase/prolidase N-terminal domain; 1.
DR InterPro; IPR007865; Aminopep_P_N.
DR InterPro; IPR029149; Creatin/AminoP/Spt16_NTD.
DR InterPro; IPR036005; Creatinase/aminopeptidase-like.
DR InterPro; IPR000994; Pept_M24.
DR PANTHER; PTHR43226; XAA-PRO AMINOPEPTIDASE 3; 1.
DR PANTHER; PTHR43226:SF4; XAA-PRO AMINOPEPTIDASE 3; 1.
DR Pfam; PF05195; AMP_N; 1.
DR Pfam; PF00557; Peptidase_M24; 1.
DR SMART; SM01011; AMP_N; 1.
DR SUPFAM; SSF55920; Creatinase/aminopeptidase; 1.
DR SUPFAM; SSF53092; Creatinase/prolidase N-terminal domain; 1.
PE 3: Inferred from homology;
KW Aminopeptidase {ECO:0000313|EMBL:SNU01924.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Manganese {ECO:0000256|ARBA:ARBA00023211};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Protease {ECO:0000313|EMBL:SNU01924.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000214750}.
FT DOMAIN 44..182
FT /note="Aminopeptidase P N-terminal"
FT /evidence="ECO:0000259|SMART:SM01011"
SQ SEQUENCE 473 AA; 51139 MW; 91A7D85E4D9F47C6 CRC64;
MTNRPPYAGT RNPRLAHVPA FREFIASGWE DVAVRPDLVP GAAEAAAEHR RRLSERLPGK
SLVLCSGVAP TRNDDCSYAF RPNSDFVWAA AGHIEDATLV LQARAGGHDA VLYMPPPFRP
GDDGFFSNAL YGELWVGATA GLSEWSEALG IEVRPRAELD SLDLHGGLAA ASVTPELAAA
LGAQHSAELD RALSQLRIVK DAWEISQLRQ AVDATVEGFA AVMREVPRAV RDGLGERWLQ
GTFDRHARTH GNGVGYSTIV GSGAHAPILH WVRCDGPIHP DAAILLDMGV EAHSLYTADV
TRTVPASGRF TEAERAVHDL VEKAHRVGMS HVRPGTQYLD FHFAAMEVIA QGLHEWGLLP
VSVDEALSPE GQHHRRYLAC GIGHHLGLDV HDCSHAQYED YMAADLVPGV VMTVEPGLYF
HANDLTLPPE LRGIGVRLED DLLVTESGAE VLSAALPIDA DGVEEWAQRH LAG
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